DAB1 DAB adaptor protein 1
Gene ID: 1600, updated on 28-Oct-2024Gene type: protein coding
Also known as: SCA37
- See all available tests in GTR for this gene
- Go to complete Gene record for DAB1
- Go to Variation Viewer for DAB1 variants
Summary
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease. GeneReviews: Not available | |
| A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly. GeneReviews: Not available | |
| Common genetic variation and the control of HIV-1 in humans. GeneReviews: Not available | |
| Genetic variants associated with disordered eating. GeneReviews: Not available | |
| Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. GeneReviews: Not available | |
| Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. GeneReviews: Not available | |
| Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. GeneReviews: Not available | |
| Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. GeneReviews: Not available | |
| Spinocerebellar ataxia type 37 | See labs |
Genomic context
- Location:
- 1p32.2-p32.1
- Sequence:
- Chromosome: 1; NC_000001.11 (56994778..58546726, complement)
- Total number of exons:
- 27
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for DAB1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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