C8orf34 chromosome 8 open reading frame 34

Gene ID: 116328, updated on 17-Sep-2024
Gene type: protein coding
Also known as: VEST1; VEST-1

Summary

This gene encodes a protein that is related to the cyclic AMP dependent protein kinase regulators. Naturally occurring mutations in this gene are associated with an increased risk for severe toxicities, such as diarrhea and neutropenia, in patients undergoing chemotherapeutic treatment. [provided by RefSeq, Mar 2017]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
A genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small-cell lung cancer. GeneReviews: Not available
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. GeneReviews: Not available
Wnt signaling and Dupuytren's disease. GeneReviews: Not available

Genomic context

Location:: 8q13.2

Sequence:: Chromosome: 8; NC_000008.11 (68330373..68819023)

Total number of exons:: 16

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for C8orf34 variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
RefSeqGene
Link to Nucleotide RefSeqGenes
Variation Viewer
Related Variants

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