SYNRG synergin gamma
Gene ID: 11276, updated on 2-Nov-2024Gene type: protein coding
Also known as: SYNG; AP1GBP1
- See all available tests in GTR for this gene
- Go to complete Gene record for SYNRG
- Go to Variation Viewer for SYNRG variants
Summary
This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. GeneReviews: Not available | |
| GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. GeneReviews: Not available |
Genomic context
- Location:
- 17q12
- Sequence:
- Chromosome: 17; NC_000017.11 (37514807..37609418, complement)
- Total number of exons:
- 24
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for SYNRG variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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