CIT citron rho-interacting serine/threonine kinase

Gene ID: 11113, updated on 10-Oct-2024
Gene type: protein coding
Also known as: CITK; CRIK; STK21; MCPH17

Summary

This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
Microcephaly 17, primary, autosomal recessive MedGen: C4310723OMIM: 617090GeneReviews: Not available	See labs

Genomic context

Location:: 12q24.23

Sequence:: Chromosome: 12; NC_000012.12 (119685791..119877320, complement)

Total number of exons:: 51

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for CIT variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
MedGen
Related information in MedGen
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
RefSeqGene
Link to Nucleotide RefSeqGenes
Variation Viewer
Related Variants

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