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TRIM16 tripartite motif containing 16

Gene ID: 10626, updated on 28-Oct-2024
Gene type: protein coding
Also known as: EBBP

Summary

The protein encoded by this gene is a tripartite motif (TRIM) family member that contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. While it lacks a RING domain found in other TRIM proteins, the encoded protein can homodimerize or heterodimerize with other TRIM proteins and has E3 ubiquitin ligase activity. This gene is also a tumor suppressor and is involved in secretory autophagy. [provided by RefSeq, Jan 2017]

Genomic context

Location:
17p12
Sequence:
Chromosome: 17; NC_000017.11 (15627966..15684311, complement)
Total number of exons:
12

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