CDX2 caudal type homeobox 2
Gene ID: 1045, updated on 27-Aug-2024Gene type: protein coding
Also known as: CDX3; CDX-3; CDX2/AS
- See all available tests in GTR for this gene
- Go to complete Gene record for CDX2
- Go to Variation Viewer for CDX2 variants
Summary
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. GeneReviews: Not available |
Genomic context
- Location:
- 13q12.2
- Sequence:
- Chromosome: 13; NC_000013.11 (27960918..27969315, complement)
- Total number of exons:
- 4
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for CDX2 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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