PARP3 poly(ADP-ribose) polymerase family member 3
Gene ID: 10039, updated on 14-Nov-2024Gene type: protein coding
Also known as: IRT1; ARTD3; ADPRT3; ADPRTL2; ADPRTL3; PADPRT-3
- See all available tests in GTR for this gene
- Go to complete Gene record for PARP3
- Go to Variation Viewer for PARP3 variants
Summary
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Genomic context
- Location:
- 3p21.2
- Sequence:
- Chromosome: 3; NC_000003.12 (51942363..51948867)
- Total number of exons:
- 11
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for PARP3 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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