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GTR Home > Conditions/Phenotypes > Spermatogenic failure 37

Spermatogenic failure 37

Summary

Spermatogenic failure-37 (SPGF37) is characterized by primary male infertility with asthenoteratozoospermia. Spermatozoa exhibit severely reduced motility due to multiple morphologic abnormalities of the flagella (MMAF), primarily consisting of short or absent flagella. Neck defects at the head-tail junction are frequently seen (Liu et al., 2019). For a general description and a discussion of genetic heterogeneity of spermatogenic failure, see SPGF1 (258150). [from OMIM]

Available tests

4 tests are in the database for this condition.

Clinical tests (4 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: IFT139A, SPGF37, STI2, Thm2, TTC21A
    Summary: tetratricopeptide repeat domain 21A

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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