Spermatogenic failure 31

Summary

SPGF31 is characterized by male infertility due to oligozoospermia with a high proportion (greater than 90%) of acephalic sperm. Affected couples may overcome infertility with intracytoplasmic sperm injection (Zhu et al., 2018). For a discussion of phenotypic and genetic heterogeneity of spermatogenic failure, see 258150. [from OMIM]

Available tests

4 tests are in the database for this condition.

Clinical tests (4 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

Associated genes Help
Genes reported to contribute to the condition.

PMFBP1
Also known as: SPGF31, STAP, PMFBP1
Summary: polyamine modulated factor 1 binding protein 1

Imported from Human Phenotype Ontology (HPO)

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Abnormality of the genitourinary system
- Acephalic spermatozoa
  Acephalic spermatozoa
  - MedGen UID: 868304
  - Concept ID: C4022698
  - Finding: Disease or Syndrome
  Abnormality of the genitourinary system
  See: Feature record | Search on this feature
- Male infertility
  Male infertility
  - MedGen UID: 5796
  - Concept ID: C0021364
  - Finding: Disease or Syndrome
  Abnormality of the genitourinary system
  See: Feature record | Search on this feature

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Clinical resources

Molecular resources

Consumer resources

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