U.S. flag

An official website of the United States government

GTR Home > Conditions/Phenotypes > Obesity due to leptin receptor gene deficiency

Obesity due to leptin receptor gene deficiency

Synonyms
Leptin receptor deficiency
Modes of inheritance
Autosomal recessive inheritance (Orphanet)

Summary

Leptin receptor deficiency is characterized by severe early-onset obesity, major hyperphagia, hypogonadotropic hypogonadism, and neuroendocrine/metabolic dysfunction (summary by Dehghani et al., 2018). [from OMIM]

Available tests

35 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Clinical tests (35 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: CD295, LEP-R, LEPRD, OB-R, OBR, LEPR
    Summary: leptin receptor

Clinical features

Help
Imported from Human Phenotype Ontology (HPO)

Show allHide all

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.