U.S. flag

An official website of the United States government

GTR Home > Conditions/Phenotypes > Alopecia universalis congenita

Alopecia universalis congenita

Synonyms
ATRICHIA, GENERALIZED
Modes of inheritance
Autosomal recessive inheritance (Orphanet)
Non-Mendelian inheritance (Orphanet)

Summary

Alopecia universalis congenita (ALUNC) is a severe autosomal recessive form of alopecia characterized by a complete absence of hair development affecting all scalp and body hair (Nothen et al., 1998). This rare disorder is clearly distinct from alopecia areata (AA1; 104000), which has an autoimmune basis with probable genetic predisposition. [from OMIM]

Available tests

12 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Clinical tests (12 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: ALUNC, AU, HSA277165, HYPT4, MUHH, MUHH1, HR
    Summary: HR lysine demethylase and nuclear receptor corepressor

Clinical features

Help
Imported from Human Phenotype Ontology (HPO)

Show allHide all

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.