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GTR Home > Conditions/Phenotypes > Lung cancer

Summary

A primary or metastatic malignant neoplasm involving the lung. [from NCI]

Genes See tests for all associated and related genes

  • Also known as: B-RAF1, B-raf, BRAF-1, BRAF1, NS7, RAFB1, BRAF
    Summary: B-Raf proto-oncogene, serine/threonine kinase

  • Also known as: ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5, CASP8
    Summary: caspase 8

  • Also known as: CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB, CYP2A6
    Summary: cytochrome P450 family 2 subfamily A member 6

  • Also known as: ERBB, ERBB1, ERRP, HER1, NISBD2, NNCIS, PIG61, mENA, EGFR
    Summary: epidermal growth factor receptor

  • Also known as: CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2), ERBB2
    Summary: erb-b2 receptor tyrosine kinase 2

  • Also known as: ARMD5, CKN2, COFS, COFS1, CSB, CSB-PGBD3, POF11, RAD26, UVSS1, ERCC6
    Summary: ERCC excision repair 6, chromatin remodeling factor

  • Also known as: ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A, FASLG
    Summary: Fas ligand

  • Also known as: IMD117, IRF-1, MAR, IRF1
    Summary: interferon regulatory factor 1

  • Also known as: 'C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2, KRAS
    Summary: KRAS proto-oncogene, GTPase

  • Also known as: AURA2, COT, EST, ESTF, MEKK8, TPL2, Tpl-2, c-COT, MAP3K8
    Summary: mitogen-activated protein kinase kinase kinase 8

  • Also known as: CCM4, CLAPO, CLOVE, CWS5, HMH, MCAP, MCM, MCMTC, PI3K, PI3K-alpha, p110-alpha, PIK3CA
    Summary: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

  • Also known as: PP2A-Abeta, PR65B, PPP2R1B
    Summary: protein phosphatase 2 scaffold subunit Abeta

  • Also known as: AR-JP, LPRS2, PARK2, PDJ, PRKN
    Summary: parkin RBR E3 ubiquitin protein ligase

  • Also known as: BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A, SLC22A18
    Summary: solute carrier family 22 member 18

Clinical features

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