Multiple symmetric lipomatosis

Synonyms

Benign symmetrical lipomatosis; Launois-Bensaude syndrome; Lipodystrophy, cephalothoracic; Lipomatosis familial benign cervical; Madelung disease; Madelung's disease

Modes of inheritance

Autosomal recessive inheritance

Autosomal recessive inheritance

MedGen UID: 141025, Concept ID: C0441748, Intellectual Product

Source: Orphanet

A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in individuals with two pathogenic alleles, either homozygotes (two copies of the same mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele).

(Orphanet)
Autosomal dominant inheritance

Autosomal dominant inheritance

MedGen UID: 141047, Concept ID: C0443147, Intellectual Product

Source: Orphanet

A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in heterozygotes. In the context of medical genetics, an autosomal dominant disorder is caused when a single copy of the mutant allele is present. Males and females are affected equally, and can both transmit the disorder with a risk of 50% for each child of inheriting the mutant allele.

(Orphanet)
Mitochondrial inheritance

Mitochondrial inheritance

MedGen UID: 165802, Concept ID: C0887941, Genetic Function

Source: Orphanet

A mode of inheritance that is observed for traits related to a gene encoded on the mitochondrial genome. Because the mitochondrial genome is essentially always maternally inherited, a mitochondrial condition can only be transmitted by females, although the condition can affect both sexes. The proportion of mutant mitochondria can vary (heteroplasmy).

(Orphanet)
Not genetically inherited

Not genetically inherited

MedGen UID: 988794, Concept ID: CN307044, Finding

Source: Orphanet

clinical entity without genetic inheritance.

(Orphanet)