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    arr aminoglycoside response regulator [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 878909, updated on 24-Aug-2024

    Summary

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    Gene symbol
    arr
    Gene description
    aminoglycoside response regulator
    Locus tag
    PA2818
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3171598..3173175, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene tRNA-Gly Neighboring gene tRNA-Gly

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pseudomonas aeruginosa, under DNA replication inhibition, tends to form biofilms via Arr. Gotoh H, et al. Res Microbiol, 2008 May. PMID 18434096
    2. Aminoglycoside antibiotics induce bacterial biofilm formation. Hoffman LR, et al. Nature, 2005 Aug 25. PMID 16121184
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results suggest that P. aeruginosa, under DNA replication stress, tends to form biofilms via Arr.
      Title: Pseudomonas aeruginosa, under DNA replication inhibition, tends to form biofilms via Arr.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables 3',5'-cyclic-nucleotide phosphodiesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of single-species biofilm formation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to antibiotic IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aminoglycoside response regulator
    NP_251508.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3171598..3173175 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_251508.1 aminoglycoside response regulator [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_251508.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9I025
      Conserved Domains (2) summary
      COG2200
      Location:262 → 517
      EAL; EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms]
      COG4943
      Location:5 → 509
      YjcC; Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain [Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version

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