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    Mipol1 mirror-image polydactyly 1 [ Mus musculus (house mouse) ]

    Gene ID: 73490, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Mipol1provided by MGI
    Official Full Name
    mirror-image polydactyly 1provided by MGI
    Primary source
    MGI:MGI:1920740
    See related
    Ensembl:ENSMUSG00000047022 AllianceGenome:MGI:1920740
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D12Ertd19e; 1700081O04Rik; 6030439O22Rik
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in nucleus. Is expressed in brain; genitourinary system; retina outer nuclear layer; and stomach. Orthologous to human MIPOL1 (mirror-image polydactyly 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 4.7), ovary adult (RPKM 4.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mipol1 in Genome Data Viewer
    Location:
    12 C1; 12 24.7 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (57277211..57546809)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (57230425..57457241)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 Neighboring gene STARR-seq mESC enhancer starr_32215 Neighboring gene STARR-seq mESC enhancer starr_32216 Neighboring gene predicted gene, 30001 Neighboring gene STARR-seq mESC enhancer starr_32218 Neighboring gene STARR-seq mESC enhancer starr_32219 Neighboring gene STARR-positive B cell enhancer ABC_E7135 Neighboring gene predicted gene, 40426 Neighboring gene phosphoribosyl pyrophosphate synthetase 1-like 3 Neighboring gene serum/glucocorticoid regulated kinase 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_32224 Neighboring gene predicted gene 16246 Neighboring gene STARR-seq mESC enhancer starr_32225 Neighboring gene predicted gene, 20016 Neighboring gene TAR DNA-binding protein 43 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    mirror-image polydactyly gene 1 protein homolog
    Names
    mirror-image polydactyly gene 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164370.2 → NP_001157842.1  mirror-image polydactyly gene 1 protein homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC122307, AC124486
      UniProtKB/TrEMBL
      E9PZ24
      Related
      ENSMUSP00000117005.2, ENSMUST00000153137.6
      Conserved Domains (2) summary
      PRK02224
      Location:69 → 297
      PRK02224; chromosome segregation protein; Provisional
      COG4372
      Location:217 → 373
      COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]

    2. NM_001422492.1 → NP_001409421.1  mirror-image polydactyly gene 1 protein homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC122307, AC124486
      Consensus CDS
      CCDS49070.1
      UniProtKB/TrEMBL
      G3UVV8
      Related
      ENSMUSP00000119636.2, ENSMUST00000123498.8

    3. NM_001422493.1 → NP_001409422.1  mirror-image polydactyly gene 1 protein homolog isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC122307, AC124486

    4. NM_001422494.1 → NP_001409423.1  mirror-image polydactyly gene 1 protein homolog isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC124486

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      57277211..57546809
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D9F8.1 GenPept UniProtKB/Swiss-Prot:Q9D9F8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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