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    Pcbp3 poly(rC) binding protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 59093, updated on 9-Nov-2024

    Summary

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    Official Symbol
    Pcbp3provided by MGI
    Official Full Name
    poly(rC) binding protein 3provided by MGI
    Primary source
    MGI:MGI:1890470
    See related
    Ensembl:ENSMUSG00000001120 AllianceGenome:MGI:1890470
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AlphaCP-3
    Summary
    Enables C-rich single-stranded DNA binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PCBP3 (poly(rC) binding protein 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 58.9), frontal lobe adult (RPKM 37.3) and 13 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Pcbp3 in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (76597688..76797951, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (76761854..76962117, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35608 Neighboring gene collagen, type VI, alpha 1 Neighboring gene STARR-seq mESC enhancer starr_27183 Neighboring gene STARR-seq mESC enhancer starr_27185 Neighboring gene STARR-seq mESC enhancer starr_27186 Neighboring gene STARR-positive B cell enhancer mm9_chr10:76424592-76424893 Neighboring gene predicted gene, 35664 Neighboring gene predicted gene, 35721 Neighboring gene STARR-seq mESC enhancer starr_27188

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Novel function of the poly(C)-binding protein alpha CP3 as a transcriptional repressor of the mu opioid receptor gene. Choi HS, et al. FASEB J, 2007 Dec. PMID 17625070
    2. Novel dual-binding function of a poly (C)-binding protein 3, transcriptional factor which binds the double-strand and single-stranded DNA sequence. Kang DH, et al. Gene, 2012 Jun 10. PMID 22521865
    3. Genomic organization of the mouse Msh4 gene producing bicistronic, chimeric and antisense mRNA. Hirano M, et al. Gene, 2004 Nov 10. PMID 15527976
    4. Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins. Makeyev AV, et al. Genomics, 2000 Aug 1. PMID 10936052
    5. Degradation of NLRP3 by p62-dependent-autophagy improves cognitive function in Alzheimer's disease by maintaining the phagocytic function of microglia. Zhang D, et al. CNS Neurosci Ther, 2023 Oct. PMID 37072933, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study demonstrates for the first time that PCBP3 can function as a repressor dependent on binding to single-strand and double-stranded poly(C) sequences.
      Title: Novel dual-binding function of a poly (C)-binding protein 3, transcriptional factor which binds the double-strand and single-stranded DNA sequence.
    2. Represses mu opioid receptor gene promoter at the transcriptional level.
      Title: Novel function of the poly(C)-binding protein alpha CP3 as a transcriptional repressor of the mu opioid receptor gene.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables C-rich single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    poly(rC)-binding protein 3
    Names
    alpha-CP3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347216.2 → NP_001334145.1  poly(rC)-binding protein 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276
      Consensus CDS
      CCDS83716.1
      UniProtKB/Swiss-Prot
      P57722
      Conserved Domains (2) summary
      cd00105
      Location:294 → 356
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    2. NM_001429299.1 → NP_001416228.1  poly(rC)-binding protein 3 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276
      UniProtKB/Swiss-Prot
      P57722, Q8BSB0, Q8C544

    3. NM_001429300.1 → NP_001416229.1  poly(rC)-binding protein 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    4. NM_001429301.1 → NP_001416230.1  poly(rC)-binding protein 3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    5. NM_001429302.1 → NP_001416231.1  poly(rC)-binding protein 3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    6. NM_001429303.1 → NP_001416232.1  poly(rC)-binding protein 3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    7. NM_001429304.1 → NP_001416233.1  poly(rC)-binding protein 3 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC168275, AC168276

    8. NM_001429305.1 → NP_001416234.1  poly(rC)-binding protein 3 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC168276

    9. NM_001429306.1 → NP_001416235.1  poly(rC)-binding protein 3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC168275, AC168276

    10. NM_001429307.1 → NP_001416236.1  poly(rC)-binding protein 3 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    11. NM_001429308.1 → NP_001416237.1  poly(rC)-binding protein 3 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC168275, AC168276

    12. NM_001429309.1 → NP_001416238.1  poly(rC)-binding protein 3 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC168276

    13. NM_001429310.1 → NP_001416239.1  poly(rC)-binding protein 3 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC168276

    14. NM_001429311.1 → NP_001416240.1  poly(rC)-binding protein 3 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC168276

    15. NM_001429312.1 → NP_001416241.1  poly(rC)-binding protein 3 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC168276

    16. NM_021568.3 → NP_067543.2  poly(rC)-binding protein 3 isoform 1

      See identical proteins and their annotated locations for NP_067543.2

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276
      Consensus CDS
      CCDS35946.2
      UniProtKB/Swiss-Prot
      P57722, Q8BSB0, Q8C544
      Related
      ENSMUSP00000001148.5, ENSMUST00000001148.11
      Conserved Domains (3) summary
      cd22519
      Location:125 → 203
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:286 → 360
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cl00098
      Location:38 → 114
      KH-I; K homology (KH) RNA-binding domain, type I

    RNA

    1. NR_152849.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC168275, AC168276
      Related
      ENSMUST00000168505.8

    2. NR_152850.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC168276

    3. NR_190709.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC168276

    4. NR_190710.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    5. NR_190711.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    6. NR_190712.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC168275, AC168276

    7. NR_190713.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC168276

    8. NR_190714.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    9. NR_190715.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    10. NR_190716.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC168276

    11. NR_190717.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC168275, AC168276

    12. NR_190718.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC168275, AC168276

    13. NR_190719.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    14. NR_190720.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC055777, AC168275, AC168276

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      76597688..76797951 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513926.4 → XP_006513989.1  poly(rC)-binding protein 3 isoform X10

      Conserved Domains (2) summary
      cd00105
      Location:274 → 336
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    2. XM_006513925.4 → XP_006513988.1  poly(rC)-binding protein 3 isoform X9

      Conserved Domains (2) summary
      cd00105
      Location:275 → 337
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    3. XM_006513922.4 → XP_006513985.1  poly(rC)-binding protein 3 isoform X4

      Conserved Domains (2) summary
      cd00105
      Location:297 → 359
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    4. XM_006513920.4 → XP_006513983.1  poly(rC)-binding protein 3 isoform X2

      Conserved Domains (4) summary
      pfam03154
      Location:181 → 314
      Atrophin-1; Atrophin-1 family
      cd22516
      Location:38 → 114
      KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22519
      Location:125 → 203
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:308 → 382
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

    5. XM_006513921.4 → XP_006513984.1  poly(rC)-binding protein 3 isoform X3

      Conserved Domains (2) summary
      cd00105
      Location:298 → 360
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    6. XM_006513916.4 → XP_006513979.1  poly(rC)-binding protein 3 isoform X1

      Conserved Domains (2) summary
      cd00105
      Location:318 → 380
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    7. XM_030245199.1 → XP_030101059.1  poly(rC)-binding protein 3 isoform X12

      Conserved Domains (3) summary
      cd22519
      Location:93 → 171
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:233 → 307
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cl00098
      Location:6 → 82
      KH-I; K homology (KH) RNA-binding domain, type I

    8. XM_030245196.2 → XP_030101056.1  poly(rC)-binding protein 3 isoform X8

      Conserved Domains (4) summary
      pfam03154
      Location:149 → 282
      Atrophin-1; Atrophin-1 family
      cd22516
      Location:6 → 82
      KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22519
      Location:93 → 171
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:276 → 350
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

    9. XM_011243517.4 → XP_011241819.1  poly(rC)-binding protein 3 isoform X7

      See identical proteins and their annotated locations for XP_011241819.1

      Conserved Domains (4) summary
      pfam03154
      Location:149 → 283
      Atrophin-1; Atrophin-1 family
      cd22516
      Location:6 → 82
      KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22519
      Location:93 → 171
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:277 → 351
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

    10. XM_036155904.1 → XP_036011797.1  poly(rC)-binding protein 3 isoform X2

      Conserved Domains (4) summary
      pfam03154
      Location:181 → 314
      Atrophin-1; Atrophin-1 family
      cd22516
      Location:38 → 114
      KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22519
      Location:125 → 203
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:308 → 382
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

    11. XM_006513919.5 → XP_006513982.1  poly(rC)-binding protein 3 isoform X1

      Conserved Domains (2) summary
      cd00105
      Location:318 → 380
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    12. XM_011243516.4 → XP_011241818.1  poly(rC)-binding protein 3 isoform X1

      See identical proteins and their annotated locations for XP_011241818.1

      Conserved Domains (2) summary
      cd00105
      Location:318 → 380
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    13. XM_030245192.2 → XP_030101052.1  poly(rC)-binding protein 3 isoform X2

      Conserved Domains (4) summary
      pfam03154
      Location:181 → 314
      Atrophin-1; Atrophin-1 family
      cd22516
      Location:38 → 114
      KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22519
      Location:125 → 203
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:308 → 382
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

    14. XM_030245190.2 → XP_030101050.1  poly(rC)-binding protein 3 isoform X1

      Conserved Domains (2) summary
      cd00105
      Location:318 → 380
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    15. XM_030245198.2 → XP_030101058.1  poly(rC)-binding protein 3 isoform X11

      Conserved Domains (3) summary
      cd22519
      Location:93 → 171
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:254 → 328
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cl00098
      Location:6 → 82
      KH-I; K homology (KH) RNA-binding domain, type I

    16. XM_030245195.2 → XP_030101055.1  poly(rC)-binding protein 3 isoform X6

      Related
      ENSMUSP00000101051.3, ENSMUST00000105411.9
      Conserved Domains (2) summary
      cd00105
      Location:294 → 356
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    17. XM_030245197.2 → XP_030101057.1  poly(rC)-binding protein 3 isoform X9

      Conserved Domains (2) summary
      cd00105
      Location:275 → 337
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    18. XM_036155906.1 → XP_036011799.1  poly(rC)-binding protein 3 isoform X5

      UniProtKB/Swiss-Prot
      P57722, Q8BSB0, Q8C544
      Conserved Domains (3) summary
      cd22519
      Location:125 → 203
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:286 → 360
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cl00098
      Location:38 → 114
      KH-I; K homology (KH) RNA-binding domain, type I

    19. XM_030245193.2 → XP_030101053.1  poly(rC)-binding protein 3 isoform X5

      UniProtKB/Swiss-Prot
      P57722, Q8BSB0, Q8C544
      Conserved Domains (3) summary
      cd22519
      Location:125 → 203
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:286 → 360
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cl00098
      Location:38 → 114
      KH-I; K homology (KH) RNA-binding domain, type I

    20. XM_036155905.1 → XP_036011798.1  poly(rC)-binding protein 3 isoform X5

      UniProtKB/Swiss-Prot
      P57722, Q8BSB0, Q8C544
      Conserved Domains (3) summary
      cd22519
      Location:125 → 203
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:286 → 360
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cl00098
      Location:38 → 114
      KH-I; K homology (KH) RNA-binding domain, type I

    21. XM_030245194.2 → XP_030101054.1  poly(rC)-binding protein 3 isoform X6

      Conserved Domains (2) summary
      cd00105
      Location:294 → 356
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    22. XM_006513917.1 → XP_006513980.1  poly(rC)-binding protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006513980.1

      Conserved Domains (2) summary
      cd00105
      Location:318 → 380
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    23. XM_006513918.1 → XP_006513981.1  poly(rC)-binding protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006513981.1

      Conserved Domains (2) summary
      cd00105
      Location:318 → 380
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    24. XM_017314038.1 → XP_017169527.1  poly(rC)-binding protein 3 isoform X5

      UniProtKB/Swiss-Prot
      P57722, Q8BSB0, Q8C544
      Related
      ENSMUSP00000129465.3, ENSMUST00000168465.9
      Conserved Domains (3) summary
      cd22519
      Location:125 → 203
      KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cd22522
      Location:286 → 360
      KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
      cl00098
      Location:38 → 114
      KH-I; K homology (KH) RNA-binding domain, type I

    25. XM_017314037.1 → XP_017169526.1  poly(rC)-binding protein 3 isoform X1

      Conserved Domains (2) summary
      cd00105
      Location:318 → 380
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    26. XM_017314036.2 → XP_017169525.1  poly(rC)-binding protein 3 isoform X1

      Conserved Domains (2) summary
      cd00105
      Location:318 → 380
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd02396
      Location:131 → 195
      PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

    RNA

    1. XR_380424.4 RNA Sequence

    2. XR_380425.4 RNA Sequence

    3. XR_871722.3 RNA Sequence

    4. XR_004936231.1 RNA Sequence

    5. XR_004936230.1 RNA Sequence

    6. XR_003948755.1 RNA Sequence

    7. XR_380422.4 RNA Sequence

    8. XR_380423.4 RNA Sequence

    9. XR_001779566.2 RNA Sequence

    10. XR_871720.3 RNA Sequence

    11. XR_004936229.1 RNA Sequence

    12. XR_003948754.1 RNA Sequence

    13. XR_380420.4 RNA Sequence

    14. XR_871719.3 RNA Sequence

    15. XR_003948756.2 RNA Sequence

    16. XR_004936232.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P57722.3 GenPept UniProtKB/Swiss-Prot:P57722

    Gene LinkOut

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