TFRC transferrin receptor [Gallus gallus (chicken)] - Gene

Summary

Symbol: TFRCprovided by CGNC
Full Name: transferrin receptorprovided by CGNC
Primary source: CGNC:49693
See related: Ensembl:ENSGALG00010015029
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: TFR2
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	9	NC_052540.1 (14630834..14645573)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	9	NC_052581.1 (14426932..14441533)

Chromosome 9 - NC_052540.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The simultaneous induction of multiple death signals from a stimulus via the TfR is of great interest to those researching cell death
Title: Simultaneous induction of apoptotic, autophagic, and necrosis-like cell death by monoclonal antibodies recognizing chicken transferrin receptor.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables transferrin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular iron ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in transferrin transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: transferrin receptor protein 1

Names: TR; tfR; tfR1; transferrin receptor (p90, CD71); transferrin receptor 2; trfr

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205256.2 → NP_990587.2 transferrin receptor protein 1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000240, X55348

UniProtKB/Swiss-Prot

Q90997

Conserved Domains (3) summary

cd02128
Location:211 → 390

PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...

pfam04253
Location:664 → 765

TFR_dimer; Transferrin receptor-like dimerization domain

cl14876
Location:398 → 626

Zinc_peptidase_like; Zinc peptidases M18, M20, M28, and M42

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

14630834..14645573

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046898330.1 → XP_046754286.1 transferrin receptor protein 1 isoform X1
XM_015291382.3 → XP_015146868.2 transferrin receptor protein 1 isoform X2

UniProtKB/Swiss-Prot

Q90997

UniProtKB/TrEMBL

A0A8V0YJE5

Related

ENSGALP00010021050.1, ENSGALT00010036210.1

Conserved Domains (2) summary

cd02128
Location:310 → 489

PA_TfR; Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 family. ...

cd09848
Location:497 → 725

M28_TfR; M28 Zn-peptidase Transferrin Receptor family