U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    GLOD5 glyoxalase domain containing 5 [ Homo sapiens (human) ]

    Gene ID: 392465, updated on 17-Sep-2024

    Summary

    Official Symbol
    GLOD5provided by HGNC
    Official Full Name
    glyoxalase domain containing 5provided by HGNC
    Primary source
    HGNC:HGNC:33358
    See related
    Ensembl:ENSG00000171433 MIM:301112; AllianceGenome:HGNC:33358
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This gene encodes a protein with a glyoxalase domain. [provided by RefSeq, Sep 2011]
    Expression
    Biased expression in duodenum (RPKM 3.2), small intestine (RPKM 2.9) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See GLOD5 in Genome Data Viewer
    Location:
    Xp11.23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (48761747..48773648)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (48172222..48184150)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (48620151..48632064)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20820 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20821 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20822 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29608 Neighboring gene SUV39H1 histone lysine methyltransferase Neighboring gene Sharpr-MPRA regulatory region 10462 Neighboring gene RNA, U6 small nuclear 1056, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29609 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29610 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29611 Neighboring gene CRISPRi-FlowFISH-validated GATA1 regulatory element 1 Neighboring gene Sharpr-MPRA regulatory region 5097 Neighboring gene ACAA2 pseudogene 1 Neighboring gene RNA, U6 small nuclear 29, pseudogene Neighboring gene CRISPRi-validated e-GATA1 enhancer Neighboring gene CRISPRi-FlowFISH-validated GATA1, HDAC6 and PLP2 regulatory element 1 Neighboring gene CRISPRi-FlowFISH-validated HDAC6, PLP2 and PQBP1 regulatory element Neighboring gene CRISPRi-FlowFISH-validated PLP2 regulatory element 5 Neighboring gene CRISPRi-FlowFISH-validated PLP2 regulatory element 6 Neighboring gene CRISPRi-FlowFISH-validated PQBP1 regulatory element 1 Neighboring gene GATA binding protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    glyoxalase domain-containing protein 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_021291.2 RefSeqGene

      Range
      5002..16903
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001080489.3NP_001073958.2  glyoxalase domain-containing protein 5

      See identical proteins and their annotated locations for NP_001073958.2

      Status: REVIEWED

      Source sequence(s)
      AC231533, AI458936, BC067236, DY655159
      Consensus CDS
      CCDS55410.1
      UniProtKB/Swiss-Prot
      A6NK44
      Related
      ENSP00000302552.6, ENST00000303227.11
      Conserved Domains (1) summary
      cd07253
      Location:35157
      GLOD5; Human glyoxalase domain-containing protein 5 and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      48761747..48773648
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      48172222..48184150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)