NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001136021.3 → NP_001129493.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform D
See identical proteins and their annotated locations for NP_001129493.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate first exon and contains an alternate exon in the 3' end compared to variant 2, that causes a frameshift. The resulting isoform (D) has shorter and distinct N- and C-termini compared to isoform C.
- Source sequence(s)
-
AK226146, AL035682, AL035684, BE674599, EU887574
- Consensus CDS
-
CCDS46614.1
- UniProtKB/Swiss-Prot
-
Q13469
- Related
- ENSP00000396471.1, ENST00000414705.5
- Conserved Domains (2) summary
-
- cd07881
Location:378 → 552
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:557 → 657
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
-
NM_001258292.2 → NP_001245221.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform E
See identical proteins and their annotated locations for NP_001245221.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate first exon compared to variant 2. The resulting isoform (E) has a shorter and distinct N-terminus compared to isoform C.
- Source sequence(s)
-
AK226146, AL035682, AL035684, BE674599
- Consensus CDS
-
CCDS68157.1
- UniProtKB/Swiss-Prot
-
Q13469
- Related
- ENSP00000477370.1, ENST00000609943.5
- Conserved Domains (2) summary
-
- cd07881
Location:378 → 552
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:557 → 657
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
-
NM_001258294.2 → NP_001245223.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform F
See identical proteins and their annotated locations for NP_001245223.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) has an alternate first exon, an alternate exon in the 3' end, and uses an alternate splice junction at the 5' end of a coding exon compared to variant 2. The resulting isoform (F) is shorter at the N-terminus and has a shorter and distinct C-terminus compared to isoform C. Variants 5 and 7 both encode the same isoform (F).
- Source sequence(s)
-
AL035682, AL035684, BE674599, EU887575
- Consensus CDS
-
CCDS68156.1
- UniProtKB/Swiss-Prot
-
Q13469
- Related
- ENSP00000477342.1, ENST00000609507.1
- Conserved Domains (2) summary
-
- cd07881
Location:179 → 353
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:358 → 458
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
-
NM_001258295.2 → NP_001245224.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform G
See identical proteins and their annotated locations for NP_001245224.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) has an alternate first exon and uses an alternate splice junction at the 5' end of a coding exon compared to variant 2. The resulting isoform (G) is shorter at the N-terminus compared to isoform C. Variants 6 and 8 both encode the same isoform (G).
- Source sequence(s)
-
AL035682, AL035684, BE674599, EU887579
- UniProtKB/TrEMBL
-
B5B2P4
- Conserved Domains (2) summary
-
- cd07881
Location:179 → 353
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:358 → 458
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
-
NM_001258296.2 → NP_001245225.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform F
See identical proteins and their annotated locations for NP_001245225.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) uses an alternate splice junction at the 5' end of a coding exon and contains an alternate exon in the 3' end compared to variant 2, that causes a frameshift. The resulting isoform (F) is shorter at the N-terminus and has a shorter and distinct C-terminus compared to isoform C. Variants 5 and 7 both encode the same isoform (F).
- Source sequence(s)
-
AL035682, BE674599, EU887576
- Consensus CDS
-
CCDS68156.1
- UniProtKB/Swiss-Prot
-
Q13469
- Related
- ENSP00000477142.1, ENST00000610033.5
- Conserved Domains (2) summary
-
- cd07881
Location:179 → 353
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:358 → 458
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
-
NM_001258297.2 → NP_001245226.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform G
See identical proteins and their annotated locations for NP_001245226.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) uses an alternate splice junction at the 5' end of a coding exon compared to variant 2. The resulting isoform (G) is shorter at the N-terminus compared to isoform C. Variants 6 and 8 both encode the same isoform (G).
- Source sequence(s)
-
AL035682, BE674599, EU887580
- UniProtKB/TrEMBL
-
B5B2P4
- Conserved Domains (2) summary
-
- cd07881
Location:179 → 353
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:358 → 458
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
-
NM_012340.5 → NP_036472.2  nuclear factor of activated T-cells, cytoplasmic 2 isoform B
See identical proteins and their annotated locations for NP_036472.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) contains an alternate exon in the 3' end compared to variant 2, that causes a frameshift. The resulting isoform (B) has a shorter and distinct C-terminus compared to isoform C.
- Source sequence(s)
-
AL035682, BE674599, EU887573, EU887576
- Consensus CDS
-
CCDS33488.1
- UniProtKB/Swiss-Prot
-
Q13469
- Related
- ENSP00000360619.3, ENST00000371564.8
- Conserved Domains (2) summary
-
- cd07881
Location:398 → 572
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:577 → 677
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
-
NM_173091.4 → NP_775114.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform C
See identical proteins and their annotated locations for NP_775114.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) encodes the longest isoform (C).
- Source sequence(s)
-
AL035682, BE674599, EU887576, EU887578
- Consensus CDS
-
CCDS13437.1
- UniProtKB/Swiss-Prot
- B5B2N8, B5B2N9, B5B2P0, B5B2P2, B5B2P3, Q13468, Q13469, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2
- Related
- ENSP00000379330.3, ENST00000396009.7
- Conserved Domains (2) summary
-
- cd07881
Location:398 → 572
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:577 → 677
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000020.11Â Reference GRCh38.p14 Primary Assembly
- Range
-
51386963..51562839 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017027851.2 → XP_016883340.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X3
-
XM_011528826.3 → XP_011527128.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X4
- Conserved Domains (2) summary
-
- cd07881
Location:179 → 353
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:358 → 458
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
-
XM_011528825.3 → XP_011527127.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X2
- Conserved Domains (2) summary
-
- cd07881
Location:378 → 552
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:557 → 657
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
-
XM_011528824.3 → XP_011527126.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X1
- Conserved Domains (2) summary
-
- cd07881
Location:398 → 572
- RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
- cd01178
Location:577 → 677
- IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
Alternate T2T-CHM13v2.0
Genomic
-
NC_060944.1Â Alternate T2T-CHM13v2.0
- Range
-
53157543..53333581 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054323454.1 → XP_054179429.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X3
-
XM_054323455.1 → XP_054179430.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X4
-
XM_054323453.1 → XP_054179428.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X2
-
XM_054323452.1 → XP_054179427.1  nuclear factor of activated T-cells, cytoplasmic 2 isoform X1