myl6 myosin, light chain 6, alkali, smooth muscle and non-muscle [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: myl6provided by ZNC
Official Full Name: myosin, light chain 6, alkali, smooth muscle and non-muscleprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041010-28
See related: Ensembl:ENSDARG00000008494 AllianceGenome:ZFIN:ZDB-GENE-041010-28
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:103624
Summary: Predicted to be a structural constituent of muscle. Predicted to be part of myosin II complex. Orthologous to human MYL6 (myosin light chain 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (39874179..39893502, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (39876643..39896018, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of muscle	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of myosin II complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: myosin light polypeptide 6

Names: myosin, light chain 6, alkali, smooth muscle and non-muscle like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001005955.1 → NP_001005955.1 myosin light polypeptide 6

See identical proteins and their annotated locations for NP_001005955.1

Status: PROVISIONAL

Source sequence(s)

BC083444

UniProtKB/TrEMBL

A0A8M1N2K8, Q5XJ62

Related

ENSDARP00000072128.4, ENSDART00000077662.6

Conserved Domains (1) summary

PTZ00184
Location:5 → 150

PTZ00184; calmodulin; Provisional

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007117.7 Reference GRCz11 Primary Assembly

Range

39874179..39893502 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005166078.5 → XP_005166135.1 myosin light polypeptide 6 isoform X2

UniProtKB/TrEMBL

A0A8M2BDM7, E9QB41

Related

ENSDARP00000116624.1, ENSDART00000135631.3

Conserved Domains (1) summary

PTZ00184
Location:5 → 150

PTZ00184; calmodulin; Provisional
XM_005166077.5 → XP_005166134.1 myosin light polypeptide 6 isoform X1

UniProtKB/TrEMBL

A0A8M2BDG5, F1QWU4

Related

ENSDARP00000108226.2, ENSDART00000130613.3

Conserved Domains (3) summary

cd00051
Location:88 → 142

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam13405
Location:11 → 40

EF-hand_6; EF-hand domain

cl08302
Location:11 → 94

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...