Slc25a29 solute carrier family 25 member 29 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc25a29provided by RGD
Official Full Name: solute carrier family 25 member 29provided by RGD
Primary source: RGD:1308104
See related: EnsemblRapid:ENSRNOG00000004351 AllianceGenome:RGD:1308104
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable acyl carnitine transmembrane transporter activity; high-affinity L-arginine transmembrane transporter activity; and high-affinity lysine transmembrane transporter activity. Predicted to be involved in L-alpha-amino acid transmembrane transport. Predicted to act upstream of or within acyl carnitine transmembrane transport and organic cation transport. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human SLC25A29 (solute carrier family 25 member 29). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 37.3), Heart (RPKM 32.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 6q32

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (133506403..133517322, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (127742027..127752915, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (132736964..132747912, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables acyl carnitine transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
NOT enables acyl carnitine transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables acyl carnitine transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
NOT enables acyl carnitine transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables basic amino acid transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables basic amino acid transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables high-affinity L-arginine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables high-affinity L-arginine transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables high-affinity L-arginine transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables high-affinity L-arginine transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables high-affinity lysine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables high-affinity lysine transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables high-affinity lysine transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables high-affinity lysine transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in L-arginine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in L-arginine transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in L-arginine transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in L-histidine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in L-histidine transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in L-histidine transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in L-lysine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in L-lysine transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in L-lysine transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in acyl carnitine transmembrane transport	IEA Inferred from Electronic Annotation more info
NOT involved_in acyl carnitine transmembrane transport	ISO Inferred from Sequence Orthology more info
NOT involved_in acyl carnitine transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within acyl carnitine transport	ISO Inferred from Sequence Orthology more info
NOT involved_in carnitine transport	ISO Inferred from Sequence Orthology more info
NOT involved_in carnitine transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial L-ornithine transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial L-ornithine transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial L-ornithine transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial L-ornithine transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in ornithine transport	ISO Inferred from Sequence Orthology more info
involved_in ornithine transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: mitochondrial basic amino acids transporter

Names: carnitine/acylcarnitine translocase-like; mitochondrial carnitine/acylcarnitine carrier protein CACL; mitochondrial ornithine transporter 3; solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29; solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001010958.1 → NP_001010958.1 mitochondrial basic amino acids transporter

See identical proteins and their annotated locations for NP_001010958.1

Status: PROVISIONAL

Source sequence(s)

BC089065

UniProtKB/Swiss-Prot

Q5HZE0

UniProtKB/TrEMBL

A0A8I6GGF5, A6KBH5

Related

ENSRNOP00000005753.6, ENSRNOT00000005753.7

Conserved Domains (2) summary

PTZ00169
Location:2 → 259

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

pfam00153
Location:88 → 175

Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086024.1 Reference GRCr8

Range

133506403..133517322 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039112402.2 → XP_038968330.1 mitochondrial basic amino acids transporter isoform X2

UniProtKB/TrEMBL

A0A8I6GGF5

Related

ENSRNOP00000111475.1, ENSRNOT00000145340.1

Conserved Domains (1) summary

pfam00153
Location:60 → 147

Mito_carr; Mitochondrial carrier protein
XM_006240541.5 → XP_006240603.1 mitochondrial basic amino acids transporter isoform X1

UniProtKB/TrEMBL

A0A8I6GGF5, A0A8L2Q298

Conserved Domains (1) summary

pfam00153
Location:92 → 179

Mito_carr; Mitochondrial carrier protein