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    LELP1 late cornified envelope like proline rich 1 [ Homo sapiens (human) ]

    Gene ID: 149018, updated on 17-Sep-2024

    Summary

    Official Symbol
    LELP1provided by HGNC
    Official Full Name
    late cornified envelope like proline rich 1provided by HGNC
    Primary source
    HGNC:HGNC:32046
    See related
    Ensembl:ENSG00000203784 MIM:611042; AllianceGenome:HGNC:32046
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Restricted expression toward testis (RPKM 182.9) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See LELP1 in Genome Data Viewer
    Location:
    1q21.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (153203430..153205120)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (152339972..152341662)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (153175906..153177596)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:153112641-153113840 Neighboring gene small proline rich protein 2C (pseudogene) Neighboring gene small proline rich protein 2G Neighboring gene uncharacterized LOC101928009 Neighboring gene proline rich 9 Neighboring gene ribosomal protein lateral stalk subunit P0 pseudogene 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    HIV-1 interactions

    Replication interactions

    Interaction Pubs
    Knockdown of late cornified envelope-like proline-rich 1 (LELP1) by siRNA enhances the early stages of HIV-1 replication in HeLa-CD4 cells infected with viral pseudotypes HIV89.6R and HIV8.2N PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    late cornified envelope-like proline-rich protein 1
    Names
    novel small proline rich protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001010857.3NP_001010857.1  late cornified envelope-like proline-rich protein 1

      See identical proteins and their annotated locations for NP_001010857.1

      Status: VALIDATED

      Source sequence(s)
      DB069578, DB086762
      Consensus CDS
      CCDS30869.1
      UniProtKB/Swiss-Prot
      A1L4E1, Q5T871
      Related
      ENSP00000357736.1, ENST00000368747.2
      Conserved Domains (1) summary
      pfam15042
      Location:185
      LELP1; Late cornified envelope-like proline-rich protein 1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      153203430..153205120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      152339972..152341662
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)