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    RTS2 Rts2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854244, updated on 2-Nov-2024

    Summary

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    Official Symbol
    RTS2
    Official Full Name
    Rts2p
    Primary source
    SGD:S000005603
    Locus tag
    YOR077W
    See related
    AllianceGenome:SGD:S000005603; FungiDB:YOR077W; VEuPathDB:YOR077W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable DNA binding activity and zinc ion binding activity. Located in cytoplasm and nucleus. Orthologous to human KIN (Kin17 DNA and RNA binding protein). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See RTS2 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (471899..472597)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Ufe1p Neighboring gene Ski7p Neighboring gene Bud21p Neighboring gene Mn(2+) transporter ATX2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The sequence of a 54.7 kb fragment of yeast chromosome XV reveals the presence of two tRNAs and 24 new open reading frames. Valens M, et al. Yeast, 1997 Mar 30. PMID 9133743
    2. Exploration of essential gene functions via titratable promoter alleles. Mnaimneh S, et al. Cell, 2004 Jul 9. PMID 15242642
    3. The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity. Goldman A, et al. Mol Cell, 2014 Aug 7. PMID 24930733, Free PMC Article
    4. Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry. Chao JT, et al. Dev Cell, 2019 Oct 21. PMID 31564614, Free PMC Article
    5. Systematic analysis of bypass suppression of essential genes. van Leeuwen J, et al. Mol Syst Biol, 2020 Sep. PMID 32939983, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Rts2p
    NP_014720.1
    • Basic zinc-finger protein; similar to human and mouse Kin17 proteins which are chromatin-associated proteins involved in UV response and DNA replication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      471899..472597
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183496.1 → NP_014720.1  TPA: Rts2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014720.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2E0, P40962
      UniProtKB/TrEMBL
      A6ZNS9, G2WMV5, N1NVR9
      Conserved Domains (2) summary
      smart00451
      Location:21 → 55
      ZnF_U1; U1-like zinc finger
      pfam10357
      Location:50 → 137
      Kin17_mid; Domain of Kin17 curved DNA-binding protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40962.1

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