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    HLA-DRB9 major histocompatibility complex, class II, DR beta 9 (pseudogene) [ Homo sapiens (human) ]

    Gene ID: 3132, updated on 2-Nov-2024

    Summary

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    Official Symbol
    HLA-DRB9provided by HGNC
    Official Full Name
    major histocompatibility complex, class II, DR beta 9 (pseudogene)provided by HGNC
    Primary source
    HGNC:HGNC:4957
    See related
    AllianceGenome:HGNC:4957
    Gene type
    pseudo
    RefSeq status
    INFERRED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    D6S206; D6S206E; HLA-DR1BL; HLA-DRB1L
    Summary
    Predicted to be involved in antigen processing and presentation and immune response. Predicted to be located in membrane. Predicted to be part of MHC class II protein complex. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See HLA-DRB9 in Genome Data Viewer
    Location:
    6p21.32
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (32459820..32460089, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (32312783..32313052, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (32427597..32427866, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene TSBP1 and BTNL2 antisense RNA 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:32382003-32382278 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:32382475-32382623 Neighboring gene HLA complex group 23 Neighboring gene butyrophilin like 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:32427819-32428319 Neighboring gene major histocompatibility complex, class II, DR alpha Neighboring gene MPRA-validated peak5756 silencer Neighboring gene major histocompatibility complex, class II, DR beta 5 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:32515949-32516448 Neighboring gene RNA, U1 small nuclear 61, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of three separated exons in the HLA class II DR region of the human major histocompatibility complex. Arvidsson AK, et al. Hum Immunol, 1995 Mar. PMID 7759314
    2. A highly diverged beta 1 exon in the DR region of the human MHC: sequence and evolutionary implications. Haas DA, et al. Immunogenetics, 1987. PMID 3102357
    3. An isolated beta 1 exon next to the DR alpha gene in the HLA-D region. Meunier HF, et al. Immunogenetics, 1986. PMID 3007347
    4. [Study on the gestational diabetes mellitus and histocompatibility human leukocyte antigen DRB allele polymorphism]. Song D, et al. Zhonghua Fu Chan Ke Za Zhi, 2002 May. PMID 12133402
    5. Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL). Franke A, et al. Nat Genet, 2010 Apr. PMID 20228798

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Observational study of gene-disease association. (HuGE Navigator)
      Title: [Study on the gestational diabetes mellitus and histocompatibility human leukocyte antigen DRB allele polymorphism].
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
    EBI GWAS Catalog
    Novel associations for hypothyroidism include known autoimmune risk loci.
    EBI GWAS Catalog

    Variation

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    See Variation Viewer (GRCh37.p13)

    General gene information

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    Markers

    Other Names

    • MHC class II antigen

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_056119.1 

      Range
      101..370
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      32459820..32460089 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_2

    Genomic

    1. NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2

      Range
      3897900..3898169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_4

    Genomic

    1. NT_167246.2 Reference GRCh38.p14 ALT_REF_LOCI_4

      Range
      3764072..3764341 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_5

    Genomic

    1. NT_167247.2 Reference GRCh38.p14 ALT_REF_LOCI_5

      Range
      3800704..3800973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_7

    Genomic

    1. NT_167249.2 Reference GRCh38.p14 ALT_REF_LOCI_7

      Range
      3775103..3775372 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      32312783..32313052 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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