gpc4.L glypican 4 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: gpc4.L
Official Full Name: glypican 4 L homeolog
Primary source: Xenbase:XB-GENE-976431
Locus tag: XELAEV_18038999mg
See related: EnsemblRapid:ENSXLAG00005018762 AllianceGenome:Xenbase:XB-GENE-976431
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: gpc4; xgly4; knypek; K-glypican
Summary: Predicted to act upstream of or within cell migration; regulation of protein localization to membrane; and regulation of signal transduction. Predicted to be located in several cellular components, including cell surface; collagen-containing extracellular matrix; and side of membrane. Is expressed in ectoderm; mesoderm; musculoskeletal system; and nervous system. Human ortholog(s) of this gene implicated in Keipert syndrome. Orthologous to human GPC4 (glypican 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8L

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (60016708..60081733, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8L	NC_030738.1 (46815155..46880248, complement)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell migration	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of protein localization to membrane	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell surface	IEA Inferred from Electronic Annotation more info
located_in collagen-containing extracellular matrix	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in side of membrane	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glypican 4 L homeolog

Names: glypican-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090719.1 → NP_001084188.1 glypican 4 L homeolog precursor

See identical proteins and their annotated locations for NP_001084188.1

Status: PROVISIONAL

Source sequence(s)

BC090231

UniProtKB/TrEMBL

A0A974H7F9, Q5EAV3, Q8AYR4

Related

ENSXLAP00005055389.1, ENSXLAT00005056594.1

Conserved Domains (1) summary

pfam01153
Location:10 → 552

Glypican; Glypican

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

60016708..60081733 complement

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GenBank, FASTA, Sequence Viewer (Graphics)