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    dcaf6.L DDB1 and CUL4 associated factor 6 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 431965, updated on 4-Nov-2024

    Summary

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    Official Symbol
    dcaf6.L
    Official Full Name
    DDB1 and CUL4 associated factor 6 L homeolog
    Primary source
    Xenbase:XB-GENE-17333738
    Locus tag
    XELAEV_18012235mg
    See related
    EnsemblRapid:ENSXLAG00005032784 AllianceGenome:Xenbase:XB-GENE-17333738
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    nrip; arcap; iqwd1; pc326; mstp055
    Summary
    Predicted to enable nuclear receptor coactivator activity. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Orthologous to human DCAF6 (DDB1 and CUL4 associated factor 6). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See dcaf6.L in Genome Data Viewer
    Location:
    chromosome: 2L
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (67573184..67685972)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (64610201..64725400)

    Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene transmembrane and coiled-coil domain family 2 L homeolog Neighboring gene zinc finger, HIT-type containing 3 L homeolog Neighboring gene piggyBac transposable element-derived protein 4-like Neighboring gene mitochondrial pyruvate carrier 2-like Neighboring gene mitochondrial pyruvate carrier 2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables nuclear receptor coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC431965

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001122878.1 → NP_001116350.1  uncharacterized protein LOC431965

      See identical proteins and their annotated locations for NP_001116350.1

      Status: PREDICTED

      Source sequence(s)
      BC124850
      UniProtKB/TrEMBL
      A0A974DM59, Q08B73
      Related
      ENSXLAP00005098663.1, ENSXLAT00005100496.1
      Conserved Domains (3) summary
      COG2319
      Location:40 → 294
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:53 → 90
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:41 → 284
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      67573184..67685972
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018244984.2 → XP_018100473.1  uncharacterized protein LOC431965 isoform X1

      UniProtKB/TrEMBL
      A0A8J0UBZ4
      Related
      ENSXLAP00005098481.1, ENSXLAT00005100304.1

    2. XM_018244986.2 → XP_018100475.1  uncharacterized protein LOC431965 isoform X3

      UniProtKB/TrEMBL
      A0A8J0UBW0

    3. XM_018244985.2 → XP_018100474.1  uncharacterized protein LOC431965 isoform X2

      UniProtKB/TrEMBL
      A0A8J0UEK2

    4. XM_041580948.1 → XP_041436882.1  uncharacterized protein LOC431965 isoform X6

      UniProtKB/TrEMBL
      A0A8J1M5B6
      Conserved Domains (2) summary
      sd00039
      Location:53 → 90
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:41 → 284
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. XM_018244987.2 → XP_018100476.1  uncharacterized protein LOC431965 isoform X4

      UniProtKB/TrEMBL
      A0A1L8HEN4, A0A974DNP3
      Related
      ENSXLAP00005098331.1, ENSXLAT00005100144.1

    6. XM_018244988.2 → XP_018100477.1  uncharacterized protein LOC431965 isoform X5

      UniProtKB/TrEMBL
      A0A8J0UAN5
      Related
      ENSXLAP00005098396.1, ENSXLAT00005100214.1
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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