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    etfb electron transfer flavoprotein subunit beta [ Danio rerio (zebrafish) ]

    Gene ID: 406271, updated on 2-Nov-2024

    Summary

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    Official Symbol
    etfbprovided by ZNC
    Official Full Name
    electron transfer flavoprotein subunit betaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1931
    See related
    Ensembl:ENSDARG00000009250 AllianceGenome:ZFIN:ZDB-GENE-040426-1931
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56177; wu:fa96b05; wu:fb02d07; wu:fb18b10
    Summary
    Predicted to enable electron transfer activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in cardiac ventricle. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Orthologous to human ETFB (electron transfer flavoprotein subunit beta). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See etfb in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (50214830..50229206, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (50010510..50024886, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene lens intrinsic membrane protein 2.5 Neighboring gene V-set and immunoglobulin domain containing 10 like Neighboring gene uncharacterized LOC137487988 Neighboring gene upstream transcription factor 2, c-fos interacting-like Neighboring gene hepcidin antimicrobial peptide

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish. Fukuda R, et al. EMBO Rep, 2020 Aug 5. PMID 32648304, Free PMC Article
    2. Flavin Adenine Dinucleotide Depletion Caused by electron transfer flavoprotein subunit alpha Haploinsufficiency Leads to Hepatic Steatosis and Injury in Zebrafish. Park KH, et al. Hepatol Commun, 2021 Jun. PMID 34141984, Free PMC Article
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables electron transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    electron transfer flavoprotein subunit beta
    Names
    electron-transfer-flavoprotein, beta polypeptide

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212998.2 → NP_998163.1  electron transfer flavoprotein subunit beta

      See identical proteins and their annotated locations for NP_998163.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045971
      UniProtKB/TrEMBL
      Q7ZV76
      Related
      ENSDARP00000017410.7, ENSDART00000010081.9
      Conserved Domains (1) summary
      COG2086
      Location:4 → 252
      FixA; Electron transfer flavoprotein, alpha and beta subunits [Energy production and conversion]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      50214830..50229206 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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