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    dlgap4a discs, large (Drosophila) homolog-associated protein 4a [ Danio rerio (zebrafish) ]

    Gene ID: 562742, updated on 14-Nov-2024

    Summary

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    Official Symbol
    dlgap4aprovided by ZNC
    Official Full Name
    discs, large (Drosophila) homolog-associated protein 4aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-080219-51
    See related
    AllianceGenome:ZFIN:ZDB-GENE-080219-51
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dlgap4; zgc:171808
    Summary
    Predicted to enable molecular adaptor activity. Predicted to be involved in modulation of chemical synaptic transmission. Predicted to act upstream of or within signaling. Predicted to be active in glutamatergic synapse and postsynaptic specialization. Orthologous to human DLGAP4 (DLG associated protein 4). [provided by Alliance of Genome Resources, Nov 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    See dlgap4a in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (42836125..43125969, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (42943521..43233354, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a Neighboring gene myosin, light chain 9a, regulatory Neighboring gene si:dkey-65j6.2 Neighboring gene transglutaminase 2, C polypeptide A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. Sundström G, et al. PLoS One, 2010 May 6. PMID 20463905, Free PMC Article
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC171808

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within signaling IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    discs, large (Drosophila) homolog-associated protein 4a; disks large-associated protein 4
    Names
    discs, large homolog-associated protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      42836125..43125969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470049.2 → XP_021325724.1  disks large-associated protein 4

      UniProtKB/TrEMBL
      A0A8M9PLE1
      Conserved Domains (1) summary
      pfam03359
      Location:713 → 1034
      GKAP; Guanylate-kinase-associated protein (GKAP) protein
    Nucleotide Protein Strain
    Heading Accession and Version

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