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    tmem59 transmembrane protein 59 [ Danio rerio (zebrafish) ]

    Gene ID: 566384, updated on 2-Nov-2024

    Summary

    Official Symbol
    tmem59provided by ZNC
    Official Full Name
    transmembrane protein 59provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070912-397
    See related
    Ensembl:ENSDARG00000019033 AllianceGenome:ZFIN:ZDB-GENE-070912-397
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkey-181m9.10
    Summary
    Predicted to be involved in positive regulation of autophagy. Predicted to be located in bounding membrane of organelle and plasma membrane. Predicted to be active in late endosome and lysosome. Orthologous to human TMEM59 (transmembrane protein 59). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See tmem59 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (26612575..26620848, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (26956941..26965243, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene Yip1 domain family, member 1 Neighboring gene leucine rich repeat containing 42 Neighboring gene U2 snRNP-associated SURP domain containing Neighboring gene uncharacterized LOC137487470 Neighboring gene microRNA 124-1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in positive regulation of autophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001111188.1NP_001104658.1  transmembrane protein 59 precursor

      See identical proteins and their annotated locations for NP_001104658.1

      Status: PROVISIONAL

      Source sequence(s)
      BC155834
      UniProtKB/TrEMBL
      A0A8M1NGT5, A9JRX6
      Related
      ENSDARP00000028016.5, ENSDART00000003946.7
      Conserved Domains (1) summary
      pfam12280
      Location:61263
      BSMAP; Brain specific membrane anchored protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      26612575..26620848 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005163400.5XP_005163457.1  transmembrane protein 59 isoform X1

      See identical proteins and their annotated locations for XP_005163457.1

      UniProtKB/TrEMBL
      B0S5J2, B3DH25
      Related
      ENSDARP00000105109.2, ENSDART00000126826.4
      Conserved Domains (1) summary
      pfam12280
      Location:61262
      BSMAP; Brain specific membrane anchored protein