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    Usp32 Ubiquitin specific protease 32 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40169, updated on 2-Nov-2024

    Summary

    Official Symbol
    Usp32provided by FlyBase
    Official Full Name
    Ubiquitin specific protease 32provided by FlyBase
    Primary source
    FLYBASE:FBgn0036913
    Locus tag
    Dmel_CG8334
    See related
    AllianceGenome:FB:FBgn0036913
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8334; Dmel\CG8334; dUSP15; Q9VW49; USP15; usp32
    Summary
    Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination. Predicted to be active in Golgi apparatus. Is expressed in adult head. Orthologous to several human genes including USP32 (ubiquitin specific peptidase 32). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See Usp32 in Genome Data Viewer
    Location:
    76D3-76D3; 3-46 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19871139..19881783)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19864239..19874883)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45433 Neighboring gene Rab8 Neighboring gene Mi-2 Neighboring gene Suppressor of Triplolethal Neighboring gene long non-coding RNA:CR32218 Neighboring gene antisense RNA:CR43889

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables cysteine-type deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ubiquitin specific protease 32
    Names
    CG8334-PF
    CG8334-PG
    CG8334-PH
    CG8334-PI
    Usp32-PF
    Usp32-PG
    Usp32-PH
    Usp32-PI
    NP_001262074.2
    NP_001262075.2
    NP_001262076.2
    NP_001262077.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19871139..19881783
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275145.2NP_001262074.2  ubiquitin specific protease 32, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      M9PD06, M9PFQ1, M9PFZ0, M9PG46
      Conserved Domains (3) summary
      COG5126
      Location:186317
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      COG5560
      Location:4861002
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cl02553
      Location:14801737
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    2. NM_001275148.2NP_001262077.2  ubiquitin specific protease 32, isoform I [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      M9PD06, M9PFQ1, M9PFZ0, M9PG46
      Conserved Domains (3) summary
      COG5126
      Location:186317
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      COG5560
      Location:4861002
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cl02553
      Location:14771734
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    3. NM_001275146.2NP_001262075.2  ubiquitin specific protease 32, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      M9PD06, M9PFQ1, M9PFZ0, M9PG46
      Conserved Domains (3) summary
      COG5126
      Location:186317
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      COG5560
      Location:4861002
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cl02553
      Location:14611718
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    4. NM_001275147.2NP_001262076.2  ubiquitin specific protease 32, isoform H [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      M9PD06, M9PFQ1, M9PFZ0, M9PG46
      Conserved Domains (3) summary
      COG5126
      Location:186317
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      COG5560
      Location:4861002
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cl02553
      Location:14581715
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...