U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    sox13.S SRY-box 13 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 397727, updated on 4-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    sox13.S
    Official Full Name
    SRY-box 13 S homeolog
    Primary source
    Xenbase:XB-GENE-865496
    Locus tag
    XELAEV_18014852mg
    See related
    EnsemblRapid:ENSXLAG00005002091 AllianceGenome:Xenbase:XB-GENE-865496
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    Sry; sox12; sox13; xSox12; xsox13; sox13.L
    Summary
    Predicted to enable sequence-specific DNA binding activity. Predicted to act upstream of or within cell fate commitment and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in cardiovascular system; nervous system; pharyngeal arch; vestibuloauditory system; and visual system. Orthologous to human SOX13 (SRY-box transcription factor 13). [provided by Alliance of Genome Resources, Nov 2024]
    Annotation information
    Annotation category: partial on reference assembly
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See sox13.S in Genome Data Viewer
    Location:
    chromosome: 2S
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (58437740..58528123, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (54404438..54495660, complement)

    Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121400540 Neighboring gene renin S homeolog Neighboring gene TATA-box binding protein associated factor 11 S homeolog Neighboring gene bridge-like lipid transfer protein family member 3AS homeolog

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Cloning and expression of Xenopus laevis xSox12 cDNA. Komatsu N, et al. Biochim Biophys Acta, 1996 Mar 1. PMID 8597594
    2. A conserved family of genes related to the testis determining gene, SRY. Denny P, et al. Nucleic Acids Res, 1992 Jun 11. PMID 1614875, Free PMC Article
    3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell fate commitment IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    transcription factor Sox-13
    Names
    SOX-12 protein
    SRY (sex determining region Y)-box 13
    SRY-box 13 L homeolog
    transcription factor Sox-12
    xSox-12

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001087769.1 → NP_001081238.1  transcription factor Sox-13

      See identical proteins and their annotated locations for NP_001081238.1

      Status: PROVISIONAL

      Source sequence(s)
      BC068647
      UniProtKB/Swiss-Prot
      P40649, Q6NUE6
      UniProtKB/TrEMBL
      A0A974DHD5
      Related
      ENSXLAP00005006288.1, ENSXLAT00005006396.1
      Conserved Domains (2) summary
      cd01388
      Location:391 → 462
      SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
      cl12013
      Location:84 → 156
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      58437740..58528123 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40649.3 GenPept UniProtKB/Swiss-Prot:P40649

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.