U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Fbxo28 F-box protein 28 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305105, updated on 17-Aug-2024

    Summary

    Official Symbol
    Fbxo28provided by RGD
    Official Full Name
    F-box protein 28provided by RGD
    Primary source
    RGD:1304584
    See related
    EnsemblRapid:ENSRNOG00000000066 AllianceGenome:RGD:1304584
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in kinetochore. Orthologous to human FBXO28 (F-box protein 28). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 145.0), Thymus (RPKM 135.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Fbxo28 in Genome Data Viewer
    Location:
    13q26
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (96527667..96553138, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (93995993..94021464, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (100715257..100740728, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108352583 Neighboring gene uncharacterized LOC108352584 Neighboring gene delta(4)-desaturase, sphingolipid 1 Neighboring gene tumor protein p53 binding protein, 2 Neighboring gene uncharacterized LOC102555308 Neighboring gene calpain 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in kinetochore ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107203.3NP_001100673.1  F-box only protein 28

      See identical proteins and their annotated locations for NP_001100673.1

      Status: VALIDATED

      Source sequence(s)
      BC167003
      UniProtKB/TrEMBL
      B2RZ28, F7EV56
      Related
      ENSRNOP00000000074.5, ENSRNOT00000000074.7
      Conserved Domains (1) summary
      pfam00646
      Location:67108
      F-box; F-box domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      96527667..96553138 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)