rhov ras homolog family member V [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rhovprovided by ZNC
Official Full Name: ras homolog family member Vprovided by ZNC
Primary source: ZFIN:ZDB-GENE-031002-10
See related: Ensembl:ENSDARG00000070434 AllianceGenome:ZFIN:ZDB-GENE-031002-10
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: sb:cb832; zgc:111951; si:ch211-244p18.1
Summary: Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within epiboly involved in gastrulation with mouth forming second and protein localization to adherens junction. Predicted to be active in plasma membrane. Is expressed in several structures, including blastoderm; notochord; segmental plate; solid lens vesicle; and yolk syncytial layer. Orthologous to human RHOV (ras homolog family member V). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (28364741..28368127)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (28465651..28469037)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in Cdc42 protein signal transduction	IBA Inferred from Biological aspect of Ancestor more info
involved_in actin filament organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in endocytosis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within epiboly involved in gastrulation with mouth forming second	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in establishment of cell polarity	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein localization to adherens junction	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within small GTPase-mediated signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: rho-related GTP-binding protein RhoV

Names: ras homolog gene family, member V

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012250.2 → NP_001012250.1 rho-related GTP-binding protein RhoV

See identical proteins and their annotated locations for NP_001012250.1

Status: PROVISIONAL

Source sequence(s)

BC154349

UniProtKB/TrEMBL

A8KC41, Q5YLG6

Related

ENSDARP00000094132.3, ENSDART00000103355.4

Conserved Domains (2) summary

cd04130
Location:30 → 193

Wrch_1; Wnt-1 responsive Cdc42 homolog (Wrch-1) is a Rho family GTPase similar to Cdc42

smart00174
Location:32 → 193

RHO; Rho (Ras homology) subfamily of Ras-like small GTPases