Krt79 keratin 79 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Krt79provided by MGI
Official Full Name: keratin 79provided by MGI
Primary source: MGI:MGI:2385030
See related: Ensembl:ENSMUSG00000061397 AllianceGenome:MGI:2385030
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable enzyme binding activity. Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be active in keratin filament. Is expressed in brain and vibrissa. Orthologous to human KRT79 (keratin 79). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in lung adult (RPKM 6.7), genital fat pad adult (RPKM 2.5) and 6 other tissues See more
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Genomic context

Location:: 15 F2; 15 57.14 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (101837767..101848759, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (101929332..101940324, complement)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

migratory keratinocytes express keratin 79 and stream out of the hair germ and into the epidermis prior to lumen formation in the embryo.
Title: Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (3) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables enzyme binding	IEA Inferred from Electronic Annotation more info
enables enzyme binding	ISO Inferred from Sequence Orthology more info
enables structural constituent of skin epidermis	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in intermediate filament organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in keratinization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in keratin filament	IBA Inferred from Biological aspect of Ancestor more info
located_in keratin filament	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: keratin, type II cytoskeletal 79

Names: CK-79; K79; cytokeratin-79; type-II keratin Kb38

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146063.1 → NP_666175.1 keratin, type II cytoskeletal 79

See identical proteins and their annotated locations for NP_666175.1

Status: PROVISIONAL

Source sequence(s)

BC031593

Consensus CDS

CCDS27867.1

UniProtKB/Swiss-Prot

Q8K2E4, Q8VED5

Related

ENSMUSP00000023799.8, ENSMUST00000023799.8

Conserved Domains (2) summary

pfam00038
Location:138 → 452

Filament; Intermediate filament protein

pfam16208
Location:62 → 135

Keratin_2_head; Keratin type II head