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    Ankmy1 ankyrin repeat and MYND domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 241158, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Ankmy1provided by MGI
    Official Full Name
    ankyrin repeat and MYND domain containing 1provided by MGI
    Primary source
    MGI:MGI:3045261
    See related
    Ensembl:ENSMUSG00000034212 AllianceGenome:MGI:3045261
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ZMYND13; 4930483I10Rik
    Summary
    Predicted to enable metal ion binding activity. Orthologous to human ANKMY1 (ankyrin repeat and MYND domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 13.4) and thymus adult (RPKM 0.8) See more
    Orthologs
    human all
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    Genomic context

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    See Ankmy1 in Genome Data Viewer
    Location:
    1 D; 1 46.6 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (92787541..92830708, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (92859840..92902987, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene glypican 1 Neighboring gene predicted gene 29480 Neighboring gene microRNA 149 Neighboring gene predicted gene, 57577 Neighboring gene RIKEN cDNA 5033417F24 gene Neighboring gene dual specificity phosphatase 28 Neighboring gene arginyl aminopeptidase (aminopeptidase B)-like 1 Neighboring gene STARR-seq mESC enhancer starr_01722

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC141406

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat and MYND domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347091.1 → NP_001334020.1  ankyrin repeat and MYND domain-containing protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC131059
      Consensus CDS
      CCDS83575.1
      UniProtKB/Swiss-Prot
      Q0IJ76, Q8C0W1
      UniProtKB/TrEMBL
      E0CYY3
      Related
      ENSMUSP00000123787.2, ENSMUST00000160548.8

    2. NM_172850.3 → NP_766438.2  ankyrin repeat and MYND domain-containing protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AK029700, BC120887
      Consensus CDS
      CCDS15178.2
      UniProtKB/Swiss-Prot
      Q0IJ76, Q8C0W1
      UniProtKB/TrEMBL
      E9PUG3
      Related
      ENSMUSP00000108622.2, ENSMUST00000112998.2
      Conserved Domains (5) summary
      cd00204
      Location:611 → 777
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam01753
      Location:940 → 980
      zf-MYND; MYND finger
      pfam02493
      Location:112 → 134
      MORN; MORN repeat
      pfam12796
      Location:724 → 826
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:720 → 754
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      92787541..92830708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529591.5 → XP_006529654.1  ankyrin repeat and MYND domain-containing protein 1 isoform X2

      Conserved Domains (5) summary
      PHA02875
      Location:595 → 836
      PHA02875; ankyrin repeat protein; Provisional
      PLN03185
      Location:83 → 184
      PLN03185; phosphatidylinositol phosphate kinase; Provisional
      sd00045
      Location:720 → 754
      ANK; ANK repeat [structural motif]
      pfam01753
      Location:940 → 980
      zf-MYND; MYND finger
      cl39094
      Location:373 → 464
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_006529590.5 → XP_006529653.1  ankyrin repeat and MYND domain-containing protein 1 isoform X1

      Conserved Domains (5) summary
      PHA02875
      Location:595 → 836
      PHA02875; ankyrin repeat protein; Provisional
      PLN03185
      Location:83 → 184
      PLN03185; phosphatidylinositol phosphate kinase; Provisional
      sd00045
      Location:720 → 754
      ANK; ANK repeat [structural motif]
      pfam01753
      Location:941 → 981
      zf-MYND; MYND finger
      cl39094
      Location:373 → 464
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_017320666.3 → XP_017176155.1  ankyrin repeat and MYND domain-containing protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q0IJ76, Q8C0W1
      Conserved Domains (4) summary
      PHA02875
      Location:446 → 687
      PHA02875; ankyrin repeat protein; Provisional
      sd00045
      Location:571 → 605
      ANK; ANK repeat [structural motif]
      pfam01753
      Location:792 → 832
      zf-MYND; MYND finger
      cl39094
      Location:224 → 315
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C0W1.1 GenPept UniProtKB/Swiss-Prot:Q8C0W1

    Gene LinkOut

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