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    BISPR BST2 interferon stimulated positive regulator [ Homo sapiens (human) ]

    Gene ID: 105221694, updated on 17-Sep-2024

    Summary

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    Official Symbol
    BISPRprovided by HGNC
    Official Full Name
    BST2 interferon stimulated positive regulatorprovided by HGNC
    Primary source
    HGNC:HGNC:51290
    See related
    Ensembl:ENSG00000282851 AllianceGenome:HGNC:51290
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    lncBST2
    Expression
    Broad expression in ovary (RPKM 23.4), lymph node (RPKM 11.3) and 17 other tissues See more
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    Genomic context

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    See BISPR in Genome Data Viewer
    Location:
    19p13.11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (17405686..17415736)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (17540421..17550483)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (17516495..17526545)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10341 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10342 Neighboring gene coiled-coil domain containing 194 Neighboring gene CRISPRi-validated cis-regulatory element chr19.2705 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:17513926-17514094 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:17515618-17516356 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14267 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14268 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14269 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14270 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14271 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:17518151-17518677 Neighboring gene bone marrow stromal cell antigen 2 Neighboring gene multivesicular body subunit 12A Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr19:17525723-17526510 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14272 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10343 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10344 Neighboring gene high mobility group box 3 pseudogene 29 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:17534662-17535187 Neighboring gene transmembrane protein 221 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10345

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Long Non-Coding RNA BST2/BISPR is Induced by IFN and Regulates the Expression of the Antiviral Factor Tetherin. Barriocanal M, et al. Front Immunol, 2014. PMID 25620967, Free PMC Article
    2. LncRNA BISPR promotes the progression of thyroid papillary carcinoma by regulating miR-21-5p. Zhang H, et al. Int J Immunopathol Pharmacol, 2018 Jan-Dec. PMID 29856242, Free PMC Article
    3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BISPR promoted the development of TPC cells by inhibiting miR-21-5p expression.
      Title: LncRNA BISPR promotes the progression of thyroid papillary carcinoma by regulating miR-21-5p.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Readthrough MVB12A

    Readthrough gene: MVB12A

    Other Names

    • BST2 IFN-stimulated positive regulator
    • BST2 interferon stimulated positive regulator (non-protein coding)
    • CTD-2521M24.9

    Clone Names

    • FLJ18422, FLJ31061

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_130765.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC010319, DA383342
      Related
      ENST00000635176.2

    2. NR_130766.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site and contains an additional segment compared to variant 1.
      Source sequence(s)
      AC010319, AK055623, HY067963
      Related
      ENST00000634675.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      17405686..17415736
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      17540421..17550483
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials