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    Trim9 tripartite motif-containing 9 [ Mus musculus (house mouse) ]

    Gene ID: 94090, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Trim9provided by MGI
    Official Full Name
    tripartite motif-containing 9provided by MGI
    Primary source
    MGI:MGI:2137354
    See related
    Ensembl:ENSMUSG00000021071 AllianceGenome:MGI:2137354
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable several functions, including SNARE binding activity; protein homodimerization activity; and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of SNARE complex assembly; negative regulation of calcium ion-dependent exocytosis; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within synaptic vesicle exocytosis. Located in cytoplasm and dendrite. Is expressed in several structures, including alimentary system; limb; nervous system; sensory organ; and urinary system. Orthologous to human TRIM9 (tripartite motif containing 9). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in frontal lobe adult (RPKM 15.7), cortex adult (RPKM 12.9) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Trim9 in Genome Data Viewer
    Location:
    12 C2; 12 29.07 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (70291307..70394404, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (70244533..70347869, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_32387 Neighboring gene liver glycogen phosphorylase Neighboring gene RIKEN cDNA F730035M05 gene Neighboring gene STARR-seq mESC enhancer starr_32388 Neighboring gene predicted gene, 38467 Neighboring gene STARR-seq mESC enhancer starr_32389 Neighboring gene predicted gene, 40435 Neighboring gene predicted gene, 51972

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. TRIM9 is specifically expressed in the embryonic and adult nervous system. Berti C, et al. Mech Dev, 2002 May. PMID 11960705
    2. The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1. McCormick LE, et al. Mol Biol Cell, 2024 May 1. PMID 38507236, Free PMC Article
    3. TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice. Zeng J, et al. Cell Rep, 2019 Apr 9. PMID 30970257, Free PMC Article
    4. MicroRNA-653 Inhibits Thymocyte Proliferation and Induces Thymocyte Apoptosis in Mice with Autoimmune Myasthenia Gravis by Downregulating TRIM9. Cao YL, et al. Neuroimmunomodulation, 2019. PMID 30703767
    5. TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies. Tanji K, et al. Neurobiol Dis, 2010 May. PMID 20085810, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.
      Title: The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.
    2. The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.
      Title: The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.
    3. MicroRNA-653 Inhibits Thymocyte Proliferation and Induces Thymocyte Apoptosis in Mice with Autoimmune Myasthenia Gravis by Downregulating TRIM9.
      Title: MicroRNA-653 Inhibits Thymocyte Proliferation and Induces Thymocyte Apoptosis in Mice with Autoimmune Myasthenia Gravis by Downregulating TRIM9.
    4. Findings reveal that TRIM9 is essential for resolving NF-kappaB-dependent neuroinflammation to promote recovery and repair after brain injury.
      Title: TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice.
    5. Authors demonstrate that tripartite motif protein 9 (TRIM9)-dependent ubiquitination of DCC blocks the interaction with and phosphorylation of FAK.
      Title: TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching.
    6. Adult-born dentate granule cells lacking Trim9 exhibited excessive dendritic arborization and mislocalization of cell bodies in vivo
      Title: Trim9 Deletion Alters the Morphogenesis of Developing and Adult-Born Hippocampal Neurons and Impairs Spatial Learning and Memory.
    7. a gradient of TRIM9-mediated ubiquitination of VASP creates a filopodial stability gradient during axon turning
      Title: The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance.
    8. TRIM9 is expressed in the mouse embryonic and adult nervous system
      Title: TRIM9 is specifically expressed in the embryonic and adult nervous system.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (3)  1 citation

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • mKIAA0282, C030048G07Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SNARE binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of SNARE complex assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of calcium ion-dependent exocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within synaptic vesicle exocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in presynaptic cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIM9
    Names
    RING-type E3 ubiquitin transferase TRIM9
    tripartite motif-containing protein 9
    NP_001103672.1
    NP_001103673.1
    NP_001273315.1
    NP_001273316.1
    NP_001273317.1
    NP_001392290.1
    NP_001392291.1
    NP_001392292.1
    NP_001392293.1
    NP_001392294.1
    NP_001392295.1
    NP_001392296.1
    NP_001392297.1
    NP_001392298.1
    NP_001392299.1
    NP_001392300.1
    NP_001392301.1
    NP_001392302.1
    NP_001392303.1
    NP_001392304.1
    NP_001392305.1
    NP_001392306.1
    NP_001392307.1
    NP_001392308.1
    NP_001392309.1
    NP_001392310.1
    NP_001392311.1
    NP_001392312.1
    NP_001392313.1
    NP_001392314.1
    NP_001392315.1
    NP_001392316.1
    NP_444397.2
    XP_006516465.1
    XP_017170752.1
    XP_017170754.1
    XP_030102867.1
    XP_036013585.1
    XP_036013586.1
    XP_036013588.1
    XP_036013589.1
    XP_036013591.1
    XP_036013592.1
    XP_036013596.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110202.2 → NP_001103672.1  E3 ubiquitin-protein ligase TRIM9 isoform 2

      See identical proteins and their annotated locations for NP_001103672.1

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      Consensus CDS
      CCDS49077.1
      UniProtKB/TrEMBL
      A0A1Y7VJX8
      Related
      ENSMUSP00000106149.3, ENSMUST00000110520.10
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:557 → 704
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    2. NM_001110203.2 → NP_001103673.1  E3 ubiquitin-protein ligase TRIM9 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      Consensus CDS
      CCDS49079.1
      UniProtKB/TrEMBL
      E9Q524
      Related
      ENSMUSP00000127081.2, ENSMUST00000167755.3
      Conserved Domains (4) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl00034
      Location:223 → 271
      Bbox_SF; B-box-type zinc finger superfamily
      cl17238
      Location:5 → 52
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    3. NM_001286386.2 → NP_001273315.1  E3 ubiquitin-protein ligase TRIM9 isoform 4

      See identical proteins and their annotated locations for NP_001273315.1

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      Consensus CDS
      CCDS88348.1
      UniProtKB/Swiss-Prot
      Q8C7M3
      Related
      ENSMUSP00000152692.2, ENSMUST00000221370.2
      Conserved Domains (4) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl00034
      Location:223 → 271
      Bbox_SF; B-box-type zinc finger superfamily
      cl17238
      Location:5 → 52
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    4. NM_001286387.2 → NP_001273316.1  E3 ubiquitin-protein ligase TRIM9 isoform 5

      See identical proteins and their annotated locations for NP_001273316.1

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      UniProtKB/TrEMBL
      A0A1Y7VJX8, Q3TR28
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:630 → 777
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    5. NM_001286388.2 → NP_001273317.1  E3 ubiquitin-protein ligase TRIM9 isoform 6

      See identical proteins and their annotated locations for NP_001273317.1

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      UniProtKB/TrEMBL
      A0A1Y7VJX8
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:631 → 796
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    6. NM_001405361.1 → NP_001392290.1  E3 ubiquitin-protein ligase TRIM9 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      UniProtKB/Swiss-Prot
      Q6ZQE5, Q80WT6, Q8C7M3, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3
      Related
      ENSMUSP00000152147.2, ENSMUST00000222316.2

    7. NM_001405362.1 → NP_001392291.1  E3 ubiquitin-protein ligase TRIM9 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    8. NM_001405363.1 → NP_001392292.1  E3 ubiquitin-protein ligase TRIM9 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    9. NM_001405364.1 → NP_001392293.1  E3 ubiquitin-protein ligase TRIM9 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    10. NM_001405365.1 → NP_001392294.1  E3 ubiquitin-protein ligase TRIM9 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    11. NM_001405366.1 → NP_001392295.1  E3 ubiquitin-protein ligase TRIM9 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    12. NM_001405367.1 → NP_001392296.1  E3 ubiquitin-protein ligase TRIM9 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    13. NM_001405368.1 → NP_001392297.1  E3 ubiquitin-protein ligase TRIM9 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    14. NM_001405369.1 → NP_001392298.1  E3 ubiquitin-protein ligase TRIM9 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    15. NM_001405370.1 → NP_001392299.1  E3 ubiquitin-protein ligase TRIM9 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    16. NM_001405371.1 → NP_001392300.1  E3 ubiquitin-protein ligase TRIM9 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      UniProtKB/TrEMBL
      A0A1Y7VP88
      Related
      ENSMUSP00000152887.2, ENSMUST00000223160.2

    17. NM_001405372.1 → NP_001392301.1  E3 ubiquitin-protein ligase TRIM9 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    18. NM_001405373.1 → NP_001392302.1  E3 ubiquitin-protein ligase TRIM9 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    19. NM_001405374.1 → NP_001392303.1  E3 ubiquitin-protein ligase TRIM9 isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    20. NM_001405375.1 → NP_001392304.1  E3 ubiquitin-protein ligase TRIM9 isoform 21

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    21. NM_001405376.1 → NP_001392305.1  E3 ubiquitin-protein ligase TRIM9 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      Related
      ENSMUSP00000152496.2, ENSMUST00000221041.2

    22. NM_001405377.1 → NP_001392306.1  E3 ubiquitin-protein ligase TRIM9 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    23. NM_001405378.1 → NP_001392307.1  E3 ubiquitin-protein ligase TRIM9 isoform 24

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    24. NM_001405379.1 → NP_001392308.1  E3 ubiquitin-protein ligase TRIM9 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      UniProtKB/TrEMBL
      A0A6I8MWZ7

    25. NM_001405380.1 → NP_001392309.1  E3 ubiquitin-protein ligase TRIM9 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      UniProtKB/TrEMBL
      A0A6I8MWZ7
      Related
      ENSMUSP00000159335.2, ENSMUST00000222603.3

    26. NM_001405381.1 → NP_001392310.1  E3 ubiquitin-protein ligase TRIM9 isoform 27

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    27. NM_001405382.1 → NP_001392311.1  E3 ubiquitin-protein ligase TRIM9 isoform 28

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    28. NM_001405383.1 → NP_001392312.1  E3 ubiquitin-protein ligase TRIM9 isoform 29

      Status: VALIDATED

      Source sequence(s)
      AC147241

    29. NM_001405384.1 → NP_001392313.1  E3 ubiquitin-protein ligase TRIM9 isoform 30

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241

    30. NM_001405385.1 → NP_001392314.1  E3 ubiquitin-protein ligase TRIM9 isoform 31

      Status: VALIDATED

      Source sequence(s)
      AC147241

    31. NM_001405386.1 → NP_001392315.1  E3 ubiquitin-protein ligase TRIM9 isoform 32

      Status: VALIDATED

      Source sequence(s)
      AC147241

    32. NM_001405387.1 → NP_001392316.1  E3 ubiquitin-protein ligase TRIM9 isoform 33

      Status: VALIDATED

      Source sequence(s)
      AC147241

    33. NM_053167.4 → NP_444397.2  E3 ubiquitin-protein ligase TRIM9 isoform 1

      See identical proteins and their annotated locations for NP_444397.2

      Status: VALIDATED

      Source sequence(s)
      AC124733, AC147241
      Consensus CDS
      CCDS49078.1
      UniProtKB/TrEMBL
      A0A1Y7VJX8, E9QLH4
      Related
      ENSMUSP00000106151.3, ENSMUST00000110522.10
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:631 → 778
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      70291307..70394404 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157695.1 → XP_036013588.1  E3 ubiquitin-protein ligase TRIM9 isoform X14

      UniProtKB/TrEMBL
      A0A1Y7VJX8
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:529 → 690
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    2. XM_030247007.2 → XP_030102867.1  E3 ubiquitin-protein ligase TRIM9 isoform X6

      UniProtKB/TrEMBL
      A0A1Y7VJX8
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:620 → 767
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    3. XM_006516402.5 → XP_006516465.1  E3 ubiquitin-protein ligase TRIM9 isoform X8

      UniProtKB/TrEMBL
      A0A1Y7VJX8
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:567 → 732
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    4. XM_036157693.1 → XP_036013586.1  E3 ubiquitin-protein ligase TRIM9 isoform X9

      UniProtKB/TrEMBL
      A0A1Y7VJX8
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:560 → 725
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    5. XM_017315265.3 → XP_017170754.1  E3 ubiquitin-protein ligase TRIM9 isoform X7

      UniProtKB/TrEMBL
      A0A1Y7VJX8
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:568 → 733
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    6. XM_017315263.3 → XP_017170752.1  E3 ubiquitin-protein ligase TRIM9 isoform X3

      UniProtKB/TrEMBL
      A0A1Y7VJX8
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:623 → 788
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    7. XM_036157692.1 → XP_036013585.1  E3 ubiquitin-protein ligase TRIM9 isoform X2

      UniProtKB/TrEMBL
      A0A1Y7VJX8
      Conserved Domains (6) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:631 → 786
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67
      cd16755
      Location:5 → 52
      RING-HC_TRIM9; RING finger, HC subclass, found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19826
      Location:223 → 271
      Bbox2_TRIM9_C-I; B-box-type 2 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins
      cd19843
      Location:166 → 212
      Bbox1_TRIM9_C-I; B-box-type 1 zinc finger found in tripartite motif-containing protein 9 (TRIM9) and similar proteins

    8. XM_036157696.1 → XP_036013589.1  E3 ubiquitin-protein ligase TRIM9 isoform X17

      Conserved Domains (3) summary
      smart00502
      Location:27 → 150
      BBC; B-Box C-terminal domain
      cd00063
      Location:204 → 283
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:382 → 547
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

    9. XM_036157699.1 → XP_036013592.1  E3 ubiquitin-protein ligase TRIM9 isoform X20

      Conserved Domains (3) summary
      smart00502
      Location:1 → 99
      BBC; B-Box C-terminal domain
      cd00063
      Location:153 → 232
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:331 → 496
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

    10. XM_036157703.1 → XP_036013596.1  E3 ubiquitin-protein ligase TRIM9 isoform X23

      Conserved Domains (3) summary
      smart00502
      Location:1 → 99
      BBC; B-Box C-terminal domain
      cd00063
      Location:153 → 232
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd12889
      Location:229 → 396
      SPRY_PRY_TRIM67_9; PRY/SPRY domain in tripartite motif-containing proteins, TRIM9 and TRIM67

    11. XM_036157698.1 → XP_036013591.1  E3 ubiquitin-protein ligase TRIM9 isoform X18

      UniProtKB/TrEMBL
      A0A6I8MWZ7
      Conserved Domains (5) summary
      smart00502
      Location:273 → 399
      BBC; B-Box C-terminal domain
      cd00063
      Location:453 → 532
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00162
      Location:10 → 49
      RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
      cl00034
      Location:223 → 271
      Bbox_SF; B-box-type zinc finger superfamily
      cl17238
      Location:5 → 52
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    RNA

    1. XR_381560.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C7M3.2 GenPept UniProtKB/Swiss-Prot:Q8C7M3

    Gene LinkOut

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