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    Gm266 predicted gene 266 [ Mus musculus (house mouse) ]

    Gene ID: 212539, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Gm266provided by MGI
    Official Full Name
    predicted gene 266provided by MGI
    Primary source
    MGI:MGI:2685112
    See related
    Ensembl:ENSMUSG00000010529 AllianceGenome:MGI:2685112
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Rap protein signal transduction and negative regulation of cell migration. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See Gm266 in Genome Data Viewer
    Location:
    12 F1; 12 61.01 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (111451043..111452257, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (111484609..111485823, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene exocyst complex component 3-like 4 Neighboring gene tumor necrosis factor, alpha-induced protein 2 Neighboring gene predicted gene, 40578 Neighboring gene STARR-positive B cell enhancer ABC_E138 Neighboring gene small nucleolar RNA, H/ACA box 28 Neighboring gene eukaryotic translation initiation factor 5 Neighboring gene RIKEN cDNA 2810029C07 gene Neighboring gene STARR-positive B cell enhancer ABC_E7187

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Georgas K, et al. Dev Biol, 2009 Aug 15. PMID 19501082
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GDP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in Rap protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC212539

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033248.3 → NP_001028420.2  uncharacterized protein LOC212539

      See identical proteins and their annotated locations for NP_001028420.2

      Status: VALIDATED

      Source sequence(s)
      BC145736, BM898567
      Consensus CDS
      CCDS26179.1
      UniProtKB/TrEMBL
      A6H634, Q3TLP2
      Related
      ENSMUSP00000010673.6, ENSMUST00000010673.7
      Conserved Domains (2) summary
      smart00010
      Location:10 → 173
      small_GTPase; Small GTPase of the Ras superfamily; ill-defined subfamily
      cl21455
      Location:11 → 172
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      111451043..111452257 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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