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    CG16865 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34788, updated on 10-May-2024

    Summary

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    Official Symbol
    CG16865provided by FlyBase
    Primary source
    FLYBASE:FBgn0028919
    Locus tag
    Dmel_CG16865
    See related
    AllianceGenome:FB:FBgn0028919
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS00941.3; Dmel\CG16865
    Summary
    Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum to Golgi vesicle-mediated transport. Part of catalytic step 2 spliceosome. Is expressed in organism. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 107. Orthologous to human STEEP1 (STING1 ER exit protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG16865 in Genome Data Viewer
    Location:
    34D1-34D1; 2-49 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13811522..13813316)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13811522..13813316)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Secretory 71 Neighboring gene Carbonic anhydrase 1 Neighboring gene Adenosine deaminase, tRNA-specific 1 Neighboring gene uncharacterized protein Neighboring gene Son of sevenless Neighboring gene black

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-Wide Association Analyses Point to Candidate Genes for Electric Shock Avoidance in Drosophila melanogaster. Appel M, et al. PLoS One, 2015. PMID 25992709, Free PMC Article
    2. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222, Free PMC Article
    3. The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub. Kwong PN, et al. J Biol Chem, 2015 Dec 11. PMID 26483546, Free PMC Article
    4. Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. Lebo MS, et al. BMC Genomics, 2009 Feb 13. PMID 19216785, Free PMC Article
    5. Genome features of "Dark-fly", a Drosophila line reared long-term in a dark environment. Izutsu M, et al. PLoS One, 2012. PMID 22432011, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum membrane organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome HDA PubMed 
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG16865-PA
    CG16865-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13811522..13813316
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273522.1 → NP_001260451.1  uncharacterized protein Dmel_CG16865, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260451.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V412
      UniProtKB/TrEMBL
      M9PD43

    2. NM_135833.4 → NP_609677.1  uncharacterized protein Dmel_CG16865, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609677.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V412
      UniProtKB/TrEMBL
      M9PD43
      Related
      FBpp0080117
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PD43 M9PD43
    Q9V412.1 Q9V412

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