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    Zfp704 zinc finger protein 704 [ Mus musculus (house mouse) ]

    Gene ID: 170753, updated on 2-Nov-2024

    Summary

    Official Symbol
    Zfp704provided by MGI
    Official Full Name
    zinc finger protein 704provided by MGI
    Primary source
    MGI:MGI:2180715
    See related
    Ensembl:ENSMUSG00000040209 AllianceGenome:MGI:2180715
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gig1; Znf704; C030026M03; C030034L19Rik
    Summary
    Enables cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; embryo mesenchyme; limb; and sensory organ. Orthologous to human ZNF704 (zinc finger protein 704). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 8.9), whole brain E14.5 (RPKM 5.2) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Zfp704 in Genome Data Viewer
    Location:
    3 A1; 3 2.31 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (9492070..9675145, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (9427010..9610085, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_06901 Neighboring gene zinc finger and BTB domain containing 10 Neighboring gene predicted gene, 41997 Neighboring gene STARR-seq mESC enhancer starr_06902 Neighboring gene VISTA enhancer mm551 Neighboring gene RIKEN cDNA C030034L19 gene Neighboring gene STARR-seq mESC enhancer starr_06904 Neighboring gene predicted gene, 54189 Neighboring gene STARR-seq mESC enhancer starr_06908 Neighboring gene STARR-seq mESC enhancer starr_06911 Neighboring gene STARR-seq mESC enhancer starr_06917 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:9633164-9633347 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:9633637-9633868 Neighboring gene STARR-seq mESC enhancer starr_06923 Neighboring gene STARR-seq mESC enhancer starr_06924 Neighboring gene STARR-seq mESC enhancer starr_06927 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:9662928-9663081 Neighboring gene STARR-positive B cell enhancer mm9_chr3:9677144-9677445 Neighboring gene predicted gene, 33169 Neighboring gene stromal cell derived factor 2 pseudogene Neighboring gene phosphoprotein associated with glycosphingolipid microdomains 1 Neighboring gene STARR-seq mESC enhancer starr_06929 Neighboring gene STARR-seq mESC enhancer starr_06930

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger protein 704
    Names
    glucocorticoid induced gene 1
    glucocorticoid-induced gene 1 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133218.2NP_573481.1  zinc finger protein 704

      See identical proteins and their annotated locations for NP_573481.1

      Status: VALIDATED

      Source sequence(s)
      AC137124, AC140312, BC052936, BP758599, CJ177621, CJ185624, DT908776
      Consensus CDS
      CCDS17234.1
      UniProtKB/Swiss-Prot
      Q7TQL8, Q8BJW9, Q9ERQ3
      Related
      ENSMUSP00000041242.8, ENSMUST00000041124.13

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      9492070..9675145 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530055.4XP_006530118.2  zinc finger protein 704 isoform X1

      UniProtKB/TrEMBL
      A0A0A6YWL6