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    SNRPN small nuclear ribonucleoprotein polypeptide N [ Homo sapiens (human) ]

    Gene ID: 6638, updated on 2-Nov-2024

    Summary

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    Official Symbol
    SNRPNprovided by HGNC
    Official Full Name
    small nuclear ribonucleoprotein polypeptide Nprovided by HGNC
    Primary source
    HGNC:HGNC:11164
    See related
    Ensembl:ENSG00000128739 MIM:182279; AllianceGenome:HGNC:11164
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SMN; PWCR; SM-D; sm-N; RT-LI; HCERN3; SNRNP-N; SNURF-SNRPN
    Summary
    This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017]
    Orthologs
    mouse all
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    Genomic context

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    See SNRPN in Genome Data Viewer
    Location:
    15q11.2
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (24823637..24978723)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (22560289..22715388)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (25068784..25223870)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene NANOG hESC enhancer GRCh37_chr15:24877390-24877896 Neighboring gene Prader-Willi region non-protein coding RNA 1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr15:24932126-24932730 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:24941505-24942052 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:24942053-24942599 Neighboring gene nuclear pore associated protein 1 Neighboring gene H3K27ac hESC enhancers GRCh37_chr15:25017418-25018314 and GRCh37_chr15:25018315-25019210 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr15:25101506-25102019 Neighboring gene Sharpr-MPRA regulatory region 849 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr15:25103559-25104072 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr15:25104073-25104585 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:25107499-25108228 Neighboring gene small nucleolar RNA U13 Neighboring gene small nucleolar RNA host gene 14 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr15:25143773-25144405 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:25145037-25145537 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr15:25196020-25196660 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:25200549-25201114 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:25201115-25201680 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:25201681-25202246 Neighboring gene ribosomal protein S27 pseudogene 2 Neighboring gene ribosomal protein L5 pseudogene 1 Neighboring gene small nucleolar RNA, C/D box 107 Neighboring gene SNRPN upstream open reading frame Neighboring gene small nucleolar RNA, C/D box 64 Neighboring gene Prader Willi/Angelman region RNA, SNRPN neighbor Neighboring gene Prader Willi/Angelman region RNA 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Functional imprinting and epigenetic modification of the human SNRPN gene. Glenn CC, et al. Hum Mol Genet, 1993 Dec. PMID 8111367
    2. The chromosome 15 imprinting centre (IC) region has undergone multiple duplication events and contains an upstream exon of SNRPN that is deleted in all Angelman syndrome patients with an IC microdeletion. Färber C, et al. Hum Mol Genet, 1999 Feb. PMID 9931342
    3. Prader-Willi syndrome is caused by disruption of the SNRPN gene. Kuslich CD, et al. Am J Hum Genet, 1999 Jan. PMID 9915945, Free PMC Article
    4. Variable methylation of the imprinted gene, SNRPN, supports a relationship between intracranial germ cell tumours and neural stem cells. Lee SH, et al. J Neurooncol, 2011 Feb. PMID 20582452
    5. In vivo nuclease hypersensitivity studies reveal multiple sites of parental origin-dependent differential chromatin conformation in the 150 kb SNRPN transcription unit. Schweizer J, et al. Hum Mol Genet, 1999 Apr. PMID 10072422

    See all (148) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-Acetylglucosamine Kinase-Small Nuclear Ribonucleoprotein Polypeptide N Interaction Promotes Axodendritic Branching in Neurons via Dynein-Mediated Microtubule Transport.
      Title: N-Acetylglucosamine Kinase-Small Nuclear Ribonucleoprotein Polypeptide N Interaction Promotes Axodendritic Branching in Neurons via Dynein-Mediated Microtubule Transport.
    2. Novel lncRNA-prader willi/angelman region RNA, SNRPN neighbour (PWARSN) aggravates tubular epithelial cell pyroptosis by regulating TXNIP via dual way in diabetic kidney disease.
      Title: Novel lncRNA-prader willi/angelman region RNA, SNRPN neighbour (PWARSN) aggravates tubular epithelial cell pyroptosis by regulating TXNIP via dual way in diabetic kidney disease.
    3. Imprinting aberrations of SNRPN, ZAC1 and INPP5F genes involved in the pathogenesis of congenital heart disease with extracardiac malformations.
      Title: Imprinting aberrations of SNRPN, ZAC1 and INPP5F genes involved in the pathogenesis of congenital heart disease with extracardiac malformations.
    4. Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability.
      Title: Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability.
    5. We focused on three important regulatory DNA elements which are all differentially methylated regions (DMRs), methylated on the maternal allele: the PWS imprinting center (PWS-IC), which is a germline DMR and the somatic NDN and MKRN3 DMRs, hierarchically controlled by PWS-IC
      Title: Loss of hierarchical imprinting regulation at the Prader-Willi/Angelman syndrome locus in human iPSCs.
    6. Methylation patterns of CpG sites within the SNRPN gene is associated with male infertility.
      Title: Novel Epigenomic Biomarkers of Male Infertility Identified by Methylation Patterns of CpG Sites Within Imprinting Control Regions of H19 and SNRPN Genes.
    7. The first study reporting an association between variability in the SNRPN gene and the risk of being obese.
      Title: Polymorphisms in the SNRPN gene are associated with obesity susceptibility in a Spanish population.
    8. we have confirmed that SNRPN methylation increases with age, which raises further questions regarding the role of SNRPN expression during the aging process.
      Title: Methylation profile of SNRPN gene and its correlation with weight and chronological age.
    9. the cases with partial loss of methylation in KCNQ1OT1 and SNRPN present clinical features different to those associated with the corresponding imprinting syndromes
      Title: In Pursuit of New Imprinting Syndromes by Epimutation Screening in Idiopathic Neurodevelopmental Disorder Patients.
    10. Knockdown of SNRPN was demonstrated to significantly inhibit medulloblastoma cell growth and induce G2/M phase arrest in vitro.
      Title: Effect of small nuclear ribonucleoprotein-associated polypeptide N on the proliferation of medulloblastoma cells.
    Submit: New GeneRIF Correction See all GeneRIFs (26)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Angelman syndrome
    MedGen: C0162635 OMIM: 105830 GeneReviews: Angelman Syndrome
    		not available
    Autism
    MedGen: C0004352 OMIM: 209850 GeneReviews: Not available
    		not available

    Copy number response

    Description
    Copy number response
    Haploinsufficency

    No evidence available (Last evaluated 2012-10-26)

    ClinGen Genome Curation Page
    Triplosensitivity

    No evidence available (Last evaluated 2012-10-26)

    ClinGen Genome Curation Page

    EBI GWAS Catalog

    Description
    Framingham Heart Study genome-wide association: results for pulmonary function measures.
    EBI GWAS Catalog
    Genome-wide association study of chronic periodontitis in a general German population.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    HIV-1 interactions

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    Protein interactions

    Protein Gene Interaction Pubs
    Vpr vpr HIV-1 Vpr is identified to have a physical interaction with small nuclear ribonucleoprotein polypeptide N (SNRPN) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ33569, FLJ36996, FLJ39265, MGC29886, DKFZp762N022, DKFZp686C0927, DKFZp761I1912, DKFZp686M12165

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables snRNP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    part_of small nuclear ribonucleoprotein complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of spliceosomal complex TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small nuclear ribonucleoprotein-associated protein N
    Names
    SM protein N
    sm protein D
    tissue-specific splicing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_012958.1 RefSeqGene

      Range
      4962..160077
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001349454.2 → NP_001336383.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) represents use of an alternate promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    2. NM_001349455.2 → NP_001336384.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) represents use of an alternate upstream promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    3. NM_001349456.2 → NP_001336385.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) represents use of an alternate upstream promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    4. NM_001349457.2 → NP_001336386.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) represents use of an alternate upstream promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    5. NM_001349458.2 → NP_001336387.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) represents use of an alternate upstream promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    6. NM_001349459.2 → NP_001336388.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) represents use of an alternate upstream promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    7. NM_001349460.2 → NP_001336389.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) represents use of an alternate upstream promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    8. NM_001349461.2 → NP_001336390.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) represents use of an alternate promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    9. NM_001349462.2 → NP_001336391.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14) represents use of an alternate promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    10. NM_001349463.2 → NP_001336392.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15) represents use of the same promoter as variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    11. NM_001349464.2 → NP_001336393.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16) represents use of the same promoter as variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    12. NM_001349465.2 → NP_001336394.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17) represents use of the same promoter as variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    13. NM_001378249.1 → NP_001365178.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18), as well as variants 1-17, encodes isoform b.
      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    14. NM_001378251.1 → NP_001365180.1  small nuclear ribonucleoprotein-associated protein N isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19) represents the longest transcript and encodes the longest isoform (a). Variants 19-23 all encode the same isoform (a).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS91965.1
      UniProtKB/TrEMBL
      Q53HE7
      Conserved Domains (1) summary
      cd01717
      Location:9 → 87
      Sm_B; Sm protein B

    15. NM_001378252.1 → NP_001365181.1  small nuclear ribonucleoprotein-associated protein N isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20), as well as variants 19 and 21-23, encodes isoform a.
      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS91965.1
      UniProtKB/TrEMBL
      Q53HE7
      Conserved Domains (1) summary
      cd01717
      Location:9 → 87
      Sm_B; Sm protein B

    16. NM_001378253.1 → NP_001365182.1  small nuclear ribonucleoprotein-associated protein N isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21), as well as variants 19, 20, 22, and 23, encodes isoform a.
      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS91965.1
      UniProtKB/TrEMBL
      Q53HE7
      Conserved Domains (1) summary
      cd01717
      Location:9 → 87
      Sm_B; Sm protein B

    17. NM_001378254.1 → NP_001365183.1  small nuclear ribonucleoprotein-associated protein N isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22), as well as variants 19-21 and 23, encodes isoform a.
      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS91965.1
      UniProtKB/TrEMBL
      Q53HE7
      Related
      ENSP00000452342.2, ENST00000554227.6
      Conserved Domains (1) summary
      cd01717
      Location:9 → 87
      Sm_B; Sm protein B

    18. NM_001378255.1 → NP_001365184.1  small nuclear ribonucleoprotein-associated protein N isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23), as well as variants 19-22, encodes isoform a.
      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS91965.1
      UniProtKB/TrEMBL
      Q53HE7
      Conserved Domains (1) summary
      cd01717
      Location:9 → 87
      Sm_B; Sm protein B

    19. NM_001378256.1 → NP_001365185.1  small nuclear ribonucleoprotein-associated protein N isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (24), as well as variant 25, encodes isoform c.
      Source sequence(s)
      AC090602, AC124312
      UniProtKB/TrEMBL
      Q53HE7
      Conserved Domains (1) summary
      cd01717
      Location:1 → 75
      Sm_B; Sm protein B

    20. NM_001378257.1 → NP_001365186.1  small nuclear ribonucleoprotein-associated protein N isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (25), as well as variant 24, encodes isoform c.
      Source sequence(s)
      AC124312
      UniProtKB/TrEMBL
      Q53HE7
      Conserved Domains (1) summary
      cd01717
      Location:1 → 75
      Sm_B; Sm protein B

    21. NM_001400634.1 → NP_001387563.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    22. NM_001400635.1 → NP_001387564.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    23. NM_001400636.1 → NP_001387565.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    24. NM_001400637.1 → NP_001387566.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    25. NM_001400638.1 → NP_001387567.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    26. NM_001400639.1 → NP_001387568.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    27. NM_001400640.1 → NP_001387569.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    28. NM_001400641.1 → NP_001387570.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    29. NM_001400643.1 → NP_001387572.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    30. NM_001400644.1 → NP_001387573.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    31. NM_001400646.1 → NP_001387575.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    32. NM_001400647.1 → NP_001387576.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    33. NM_001400649.1 → NP_001387578.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    34. NM_001400650.1 → NP_001387579.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    35. NM_001400652.1 → NP_001387581.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    36. NM_001400683.1 → NP_001387612.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    37. NM_001400684.1 → NP_001387613.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    38. NM_001400685.1 → NP_001387614.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    39. NM_001400686.1 → NP_001387615.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    40. NM_001400687.1 → NP_001387616.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    41. NM_001400688.1 → NP_001387617.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    42. NM_001400689.1 → NP_001387618.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    43. NM_001400690.1 → NP_001387619.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    44. NM_001400691.1 → NP_001387620.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    45. NM_001400692.1 → NP_001387621.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00
      Related
      ENSP00000495345.1, ENST00000642807.1

    46. NM_001400693.1 → NP_001387622.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00
      Related
      ENSP00000494831.1, ENST00000645002.1

    47. NM_001400694.1 → NP_001387623.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    48. NM_001400695.1 → NP_001387624.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    49. NM_001400696.1 → NP_001387625.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    50. NM_001400697.1 → NP_001387626.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    51. NM_001400698.1 → NP_001387627.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    52. NM_001400701.1 → NP_001387630.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    53. NM_001400702.1 → NP_001387631.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    54. NM_001400703.1 → NP_001387632.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    55. NM_001400704.1 → NP_001387633.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    56. NM_001400706.1 → NP_001387635.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    57. NM_001400708.1 → NP_001387637.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    58. NM_001400710.1 → NP_001387639.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    59. NM_001400712.1 → NP_001387641.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    60. NM_001400713.1 → NP_001387642.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    61. NM_001400715.1 → NP_001387644.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    62. NM_001400716.1 → NP_001387645.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    63. NM_001400717.1 → NP_001387646.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    64. NM_001400718.1 → NP_001387647.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    65. NM_001400719.1 → NP_001387648.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    66. NM_001400720.1 → NP_001387649.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    67. NM_001400721.1 → NP_001387650.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    68. NM_001400722.1 → NP_001387651.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    69. NM_001400723.1 → NP_001387652.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    70. NM_001400724.1 → NP_001387653.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    71. NM_001400725.1 → NP_001387654.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    72. NM_001400726.1 → NP_001387655.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    73. NM_001400727.1 → NP_001387656.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00
      Related
      ENSP00000306223.10, ENST00000346403.10

    74. NM_001400728.1 → NP_001387657.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00
      Related
      ENSP00000463458.1, ENST00000577565.1

    75. NM_001400729.1 → NP_001387658.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    76. NM_001400730.1 → NP_001387659.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    77. NM_001400731.1 → NP_001387660.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    78. NM_001400732.1 → NP_001387661.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    79. NM_001400733.1 → NP_001387662.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    80. NM_001400734.1 → NP_001387663.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    81. NM_001400735.1 → NP_001387664.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    82. NM_001400736.1 → NP_001387665.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    83. NM_001400737.1 → NP_001387666.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    84. NM_001400738.1 → NP_001387667.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    85. NM_001400739.1 → NP_001387668.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    86. NM_001400740.1 → NP_001387669.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    87. NM_001400741.1 → NP_001387670.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    88. NM_001400742.1 → NP_001387671.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    89. NM_001400743.1 → NP_001387672.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    90. NM_001400744.1 → NP_001387673.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    91. NM_001400745.1 → NP_001387674.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    92. NM_001400746.1 → NP_001387675.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    93. NM_001400747.1 → NP_001387676.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    94. NM_001400748.1 → NP_001387677.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    95. NM_001400753.1 → NP_001387682.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    96. NM_001400754.1 → NP_001387683.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    97. NM_001400755.1 → NP_001387684.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    98. NM_001400756.1 → NP_001387685.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    99. NM_001400757.1 → NP_001387686.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    100. NM_001400758.1 → NP_001387687.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    101. NM_001400759.1 → NP_001387688.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    102. NM_001400762.1 → NP_001387691.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    103. NM_001400763.1 → NP_001387692.1  small nuclear ribonucleoprotein-associated protein N isoform b

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      X5DP00

    104. NM_001400764.1 → NP_001387693.1  small nuclear ribonucleoprotein-associated protein N isoform d

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312

    105. NM_001400765.1 → NP_001387694.1  small nuclear ribonucleoprotein-associated protein N isoform d

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312

    106. NM_001400767.1 → NP_001387696.1  small nuclear ribonucleoprotein-associated protein N isoform c

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312

    107. NM_001400768.1 → NP_001387697.1  small nuclear ribonucleoprotein-associated protein N isoform e

      Status: REVIEWED

      Source sequence(s)
      AC090602, AC124312

    108. NM_003097.6 → NP_003088.1  small nuclear ribonucleoprotein-associated protein N isoform b

      See identical proteins and their annotated locations for NP_003088.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) is the predominant splice variant and initiates at the imprinting center. This splice variant is bicistronic and can also encode the SNURF protein from an upstream open reading frame. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Related
      ENSP00000375105.4, ENST00000390687.9
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    109. NM_022805.5 → NP_073716.1  small nuclear ribonucleoprotein-associated protein N isoform b

      See identical proteins and their annotated locations for NP_073716.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) represents use of an alternate promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Related
      ENSP00000382969.1, ENST00000400097.5
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    110. NM_022806.5 → NP_073717.1  small nuclear ribonucleoprotein-associated protein N isoform b

      See identical proteins and their annotated locations for NP_073717.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) represents use of an alternate upstream promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    111. NM_022807.5 → NP_073718.1  small nuclear ribonucleoprotein-associated protein N isoform b

      See identical proteins and their annotated locations for NP_073718.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) represents use of an alternate upstream promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Related
      ENSP00000382972.1, ENST00000400100.5
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    112. NM_022808.5 → NP_073719.1  small nuclear ribonucleoprotein-associated protein N isoform b

      See identical proteins and their annotated locations for NP_073719.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) represents use of an alternate upstream promoter compared to variant 1. Variants 1-18 all encode the same isoform (b).
      Source sequence(s)
      AC090602, AC090983, AC124312
      Consensus CDS
      CCDS10017.1
      UniProtKB/Swiss-Prot
      B3KVR1, P14648, P17135, P63162, Q0D2Q5
      UniProtKB/TrEMBL
      Q53HE7, X5DP00
      Conserved Domains (1) summary
      cd01717
      Location:5 → 83
      Sm_B; Sm protein B

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      24823637..24978723
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      22560289..22715388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P63162.1 GenPept UniProtKB/Swiss-Prot:P63162

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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