dcaf17 ddb1 and cul4 associated factor 17 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dcaf17provided by ZNC
Official Full Name: ddb1 and cul4 associated factor 17provided by ZNC
Primary source: ZFIN:ZDB-GENE-071008-1
See related: Ensembl:ENSDARG00000074909 AllianceGenome:ZFIN:ZDB-GENE-071008-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: c2orf37
Summary: Predicted to be involved in protein ubiquitination. Predicted to be located in membrane and nucleolus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Human ortholog(s) of this gene implicated in Woodhouse-Sakati syndrome. Orthologous to human DCAF17 (DDB1 and CUL4 associated factor 17). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (3499080..3519767, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (3527555..3548188, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Cul4-RING E3 ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Cul4-RING E3 ubiquitin ligase complex	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: DDB1- and CUL4-associated factor 17

Names: protein C2orf37 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001144789.1 → NP_001138261.1 DDB1- and CUL4-associated factor 17

See identical proteins and their annotated locations for NP_001138261.1

Status: PROVISIONAL

Source sequence(s)

BX248116

UniProtKB/Swiss-Prot

A8WHR0

Related

ENSDARP00000121682.1, ENSDART00000145043.3

Conserved Domains (1) summary

pfam15802
Location:44 → 518

DCAF17; DDB1- and CUL4-associated factor 17

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007120.7 Reference GRCz11 Primary Assembly

Range

3499080..3519767 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_068223398.1 → XP_068079499.1 DDB1- and CUL4-associated factor 17 isoform X2
XM_068223397.1 → XP_068079498.1 DDB1- and CUL4-associated factor 17 isoform X2
XM_068223396.1 → XP_068079497.1 DDB1- and CUL4-associated factor 17 isoform X1
XM_068223395.1 → XP_068079496.1 DDB1- and CUL4-associated factor 17 isoform X1
XM_017357683.3 → XP_017213172.1 DDB1- and CUL4-associated factor 17 isoform X1

UniProtKB/TrEMBL

A0A0R4IWT1, A0A8M6Z0X3

Related

ENSDARP00000139615.2, ENSDART00000169586.2

Conserved Domains (1) summary

pfam15802
Location:44 → 518

DCAF17; DDB1- and CUL4-associated factor 17