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    CREB1 cAMP responsive element binding protein 1 [ Homo sapiens (human) ]

    Gene ID: 1385, updated on 3-Nov-2024

    Summary

    Official Symbol
    CREB1provided by HGNC
    Official Full Name
    cAMP responsive element binding protein 1provided by HGNC
    Primary source
    HGNC:HGNC:2345
    See related
    Ensembl:ENSG00000118260 MIM:123810; AllianceGenome:HGNC:2345
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CREB; CREB-1
    Summary
    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
    Expression
    Ubiquitous expression in lymph node (RPKM 5.0), thyroid (RPKM 4.7) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CREB1 in Genome Data Viewer
    Location:
    2q33.3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (207529962..207605988)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (208003958..208080006)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (208394686..208470712)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17035 Neighboring gene uncharacterized LOC105373851 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr2:208259108-208260307 Neighboring gene NANOG hESC enhancer GRCh37_chr2:208265954-208266524 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17036 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17037 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12275 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17038 Neighboring gene uncharacterized LOC124907970 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17039 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12276 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12277 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17040 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17041 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12279 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12278 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12280 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:208396403-208396904 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:208396905-208397404 Neighboring gene methyltransferase 21A, HSPA lysine Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17042 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12281 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:208490584-208491288 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:208491289-208491991 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:208537981-208538753 Neighboring gene long intergenic non-protein coding RNA 1857 Neighboring gene ribosomal protein S29 pseudogene 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Angiomatoid fibrous histiocytoma
    MedGen: C1266127 OMIM: 612160 GeneReviews: Not available
    Compare labs

    EBI GWAS Catalog

    Description
    Genome-wide genetic and transcriptomic investigation of variation in antibody response to dietary antigens.
    EBI GWAS Catalog

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp120 env HIV-1 gp120-induced neuron death is inhibited by CCL3L1 treatment via the phosphorylation of CREB, the upregulation of Bcl-2, and the PKA and CaMKI/CaMKIV cell signaling pathways PubMed
    Tat tat HIV-1 Tat induces upregulation of HDAC2 expression and downregulation of CREB and CaMKIIa expression in human neuroblastoma SK-N-MC cells PubMed
    tat The function and activity of CREB is required for both Tat-induced Rho signaling and nuclear targeting of ZO-1 PubMed
    tat HIV-1 Tat increases both CREB phosphorylation and DNA binding by 7- to 10-fold within 2 hours after stimulation in hematopoietic progenitor cells PubMed
    tat Tat-induced IL-10 expression is regulated by p38 MAPK- and CaMK II-activated CREB-1 as well as Sp-1 transcription factors PubMed
    tat The CKLF-like MARVEL transmembrane domain-containing family 2 (CMTM2) blocks HIV-1 Tat-induced AP-1 and CREB activation, which leads to suppress HIV-1 provirus transcription PubMed
    tat HIV-1 Tat upregulates IL-10 synthesis by ERK MAPK-dependent CREB-1 transcription factor activation through Ser(133) phosphorylation PubMed
    tat HIV-1 Tat protein downregulates the Ser-133 phosphorylation, activation, and expression of CREB transcription factor in PC12 neuronal cells through sequential activation of phosphatidylinositol 3-kinase, AKT, and cyclic nucleoside phosphodiesterases PubMed
    tat Extracellular HIV-1 Tat protein induces the rapid Ser-133 phosphorylation and activation of CREB transcription factor in lymphoid cells through a signal cascade involving the MAPK pathway PubMed
    Vpr vpr The RNA and protein levels of cAMP responsive element binding protein (CREB) decreases in Vpr-treated human neurons compared to the untreated control PubMed
    matrix gag HIV-1 MA increases phosphorylation and the DNA-binding activity of CREB and c-Myc through activation of the cAMP/PKA and MEK/ERK signaling pathways. Both signaling pathways are synergistically activated upon co-stimulation through the CD19 receptor PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC9284

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
    Inferred from Sequence Alignment
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables cAMP response element binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cAMP response element binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables sequence-specific double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in axonogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cAMP-mediated signaling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to forskolin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to hepatocyte growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to leukemia inhibitory factor IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to retinoic acid ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cellular response to zinc ion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in circadian rhythm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in hormone secretion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lactation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lung saccule development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in memory IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of transcription by competitive promoter binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in osteoclast differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in pituitary gland development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of cardiac muscle tissue development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of fat cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of hormone secretion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of lipid biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of multicellular organism growth IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of osteoclast differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein stabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of cell size IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of testosterone biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in response to glucagon ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in response to purine-containing compound IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in response to xenobiotic stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in secretory granule organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in type I pneumocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of ATF4-CREB1 transcription factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ATF4-CREB1 transcription factor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of RNA polymerase II transcription regulator complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of RNA polymerase II transcription regulator complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromatin ISA
    Inferred from Sequence Alignment
    more info
     
    located_in euchromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    cyclic AMP-responsive element-binding protein 1
    Names
    active transcription factor CREB
    cAMP-response element-binding protein-1
    cyclic adenosine 3',5'-monophosphate response element binding protein
    cyclic adenosine 3',5'-monophosphate response element-binding protein CREB
    transactivator protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_023299.1 RefSeqGene

      Range
      5071..81097
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001320793.2 → NP_001307722.1  cyclic AMP-responsive element-binding protein 1 isoform C

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon and differs in the 3' UTR and coding sequence compared to variant 2. The resulting isoform (C) lacks an alternate internal segment and has a shorter and distinct C-terminus compared to isoform B.
      Source sequence(s)
      AC009298, AK298740, DC366797
      UniProtKB/TrEMBL
      B7Z5C6
      Conserved Domains (1) summary
      pfam02173
      Location:99 → 137
      pKID; pKID domain
    2. NM_001371426.1 → NP_001358355.1  cyclic AMP-responsive element-binding protein 1 isoform B

      Status: REVIEWED

      Source sequence(s)
      AC009298, AC079767
      Consensus CDS
      CCDS2375.1
      UniProtKB/TrEMBL
      A0A024R401, Q4ZG78, Q5U0J5
      Conserved Domains (2) summary
      cd14690
      Location:285 → 339
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:113 → 151
      pKID; pKID domain
    3. NM_001371427.1 → NP_001358356.1  cyclic AMP-responsive element-binding protein 1 isoform A

      Status: REVIEWED

      Source sequence(s)
      AC009298, AC079767
      Consensus CDS
      CCDS2374.1
      UniProtKB/Swiss-Prot
      P16220, P21934, Q6V963, Q9UMA7
      UniProtKB/TrEMBL
      A0A024R437, Q4ZG78, Q53X93
      Related
      ENSP00000405539.1, ENST00000430624.5
      Conserved Domains (2) summary
      cd14690
      Location:271 → 325
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:99 → 137
      pKID; pKID domain
    4. NM_001371428.1 → NP_001358357.1  cyclic AMP-responsive element-binding protein 1 isoform D

      Status: REVIEWED

      Source sequence(s)
      AC009298, AC079767
      UniProtKB/TrEMBL
      C9J896
      Related
      ENSP00000405711.1, ENST00000448277.5
      Conserved Domains (2) summary
      cd14690
      Location:231 → 285
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:59 → 97
      pKID; pKID domain
    5. NM_004379.5 → NP_004370.1  cyclic AMP-responsive element-binding protein 1 isoform A

      See identical proteins and their annotated locations for NP_004370.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1, also known as A) lacks an alternate in-frame exon compared to variant 2. The resulting isoform (A) has the same N- and C-termini but is shorter compared to isoform B.
      Source sequence(s)
      AC079767, BC095407, BU154326
      Consensus CDS
      CCDS2374.1
      UniProtKB/Swiss-Prot
      P16220, P21934, Q6V963, Q9UMA7
      UniProtKB/TrEMBL
      A0A024R437, Q4ZG78, Q53X93
      Related
      ENSP00000236995.3, ENST00000353267.8
      Conserved Domains (2) summary
      cd14690
      Location:271 → 325
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:99 → 137
      pKID; pKID domain
    6. NM_134442.5 → NP_604391.1  cyclic AMP-responsive element-binding protein 1 isoform B

      See identical proteins and their annotated locations for NP_604391.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2, also known as B) represents the longest transcript and encodes the longest isoform (B).
      Source sequence(s)
      AC079767, BC010636, BU154326, DC366797
      Consensus CDS
      CCDS2375.1
      UniProtKB/TrEMBL
      A0A024R401, Q4ZG78, Q5U0J5
      Related
      ENSP00000387699.2, ENST00000432329.6
      Conserved Domains (2) summary
      cd14690
      Location:285 → 339
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:113 → 151
      pKID; pKID domain

    RNA

    1. NR_135473.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an alternate segment in the 3' end compared to variant 2. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC079767, BC010636, BU154326, DC366797, HY204508
    2. NR_163946.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC009298, AC079767
    3. NR_163947.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC009298, AC079767

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      207529962..207605988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011510646.4 → XP_011508948.1  cyclic AMP-responsive element-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      Q4ZG78
      Conserved Domains (1) summary
      pfam02173
      Location:113 → 151
      pKID; pKID domain
    2. XM_047443437.1 → XP_047299393.1  cyclic AMP-responsive element-binding protein 1 isoform X3

    3. XM_047443436.1 → XP_047299392.1  cyclic AMP-responsive element-binding protein 1 isoform X3

    4. XM_011510648.4 → XP_011508950.1  cyclic AMP-responsive element-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      Q4ZG78
      Conserved Domains (1) summary
      pfam02173
      Location:113 → 151
      pKID; pKID domain
    5. XM_017003399.3 → XP_016858888.1  cyclic AMP-responsive element-binding protein 1 isoform X6

      UniProtKB/TrEMBL
      Q4ZG78
    6. XM_047443438.1 → XP_047299394.1  cyclic AMP-responsive element-binding protein 1 isoform X4

    7. XM_047443440.1 → XP_047299396.1  cyclic AMP-responsive element-binding protein 1 isoform X7

    8. XM_047443439.1 → XP_047299395.1  cyclic AMP-responsive element-binding protein 1 isoform X7

    9. XM_047443441.1 → XP_047299397.1  cyclic AMP-responsive element-binding protein 1 isoform X8

    10. XM_047443442.1 → XP_047299398.1  cyclic AMP-responsive element-binding protein 1 isoform X9

      Related
      ENSP00000407227.1, ENST00000445803.5
    11. XM_047443443.1 → XP_047299399.1  cyclic AMP-responsive element-binding protein 1 isoform X10

    12. XM_047443435.1 → XP_047299391.1  cyclic AMP-responsive element-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A024R401, Q5U0J5
    13. XM_011510650.4 → XP_011508952.1  cyclic AMP-responsive element-binding protein 1 isoform X5

      See identical proteins and their annotated locations for XP_011508952.1

      UniProtKB/TrEMBL
      C9J896
      Conserved Domains (2) summary
      cd14690
      Location:245 → 299
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:73 → 111
      pKID; pKID domain
    14. XM_047443444.1 → XP_047299400.1  cyclic AMP-responsive element-binding protein 1 isoform X11

    15. XM_017003401.3 → XP_016858890.1  cyclic AMP-responsive element-binding protein 1 isoform X12

      Conserved Domains (1) summary
      cd14690
      Location:55 → 109
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      208003958..208080006
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054340614.1 → XP_054196589.1  cyclic AMP-responsive element-binding protein 1 isoform X2

    2. XM_054340616.1 → XP_054196591.1  cyclic AMP-responsive element-binding protein 1 isoform X3

    3. XM_054340615.1 → XP_054196590.1  cyclic AMP-responsive element-binding protein 1 isoform X3

    4. XM_054340617.1 → XP_054196592.1  cyclic AMP-responsive element-binding protein 1 isoform X4

    5. XM_054340620.1 → XP_054196595.1  cyclic AMP-responsive element-binding protein 1 isoform X6

    6. XM_054340618.1 → XP_054196593.1  cyclic AMP-responsive element-binding protein 1 isoform X4

    7. XM_054340622.1 → XP_054196597.1  cyclic AMP-responsive element-binding protein 1 isoform X7

    8. XM_054340621.1 → XP_054196596.1  cyclic AMP-responsive element-binding protein 1 isoform X7

    9. XM_054340623.1 → XP_054196598.1  cyclic AMP-responsive element-binding protein 1 isoform X8

    10. XM_054340624.1 → XP_054196599.1  cyclic AMP-responsive element-binding protein 1 isoform X9

    11. XM_054340625.1 → XP_054196600.1  cyclic AMP-responsive element-binding protein 1 isoform X10

    12. XM_054340613.1 → XP_054196588.1  cyclic AMP-responsive element-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A024R401, Q5U0J5
    13. XM_054340619.1 → XP_054196594.1  cyclic AMP-responsive element-binding protein 1 isoform X5

    14. XM_054340626.1 → XP_054196601.1  cyclic AMP-responsive element-binding protein 1 isoform X11

    15. XM_054340627.1 → XP_054196602.1  cyclic AMP-responsive element-binding protein 1 isoform X12