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    Rer1 retention in endoplasmic reticulum sorting receptor 1 [ Mus musculus (house mouse) ]

    Gene ID: 67830, updated on 28-Oct-2024

    Summary

    Official Symbol
    Rer1provided by MGI
    Official Full Name
    retention in endoplasmic reticulum sorting receptor 1provided by MGI
    Primary source
    MGI:MGI:1915080
    See related
    Ensembl:ENSMUSG00000029048 AllianceGenome:MGI:1915080
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110060F11Rik; 5830454N22Rik
    Summary
    Enables acetylcholine receptor binding activity. Acts upstream of or within positive regulation of protein localization to plasma membrane and skeletal muscle acetylcholine-gated channel clustering. Located in cell surface and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human RER1 (retention in endoplasmic reticulum sorting receptor 1). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 58.8), bladder adult (RPKM 46.9) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rer1 in Genome Data Viewer
    Location:
    4 E2; 4 86.17 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (155158566..155170840, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (155074109..155086371, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene phospholipase C, eta 2 Neighboring gene STARR-positive B cell enhancer ABC_E10295 Neighboring gene STARR-positive B cell enhancer ABC_E1295 Neighboring gene peroxisomal biogenesis factor 10 Neighboring gene MORN repeat containing 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:154500916-154501099 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:154524494-154524677 Neighboring gene STARR-positive B cell enhancer mm9_chr4:154536903-154537203 Neighboring gene STARR-seq mESC enhancer starr_12252 Neighboring gene ski sarcoma viral oncogene homolog (avian) Neighboring gene STARR-seq mESC enhancer starr_12254 Neighboring gene predicted gene, 42364

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables acetylcholine receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum-Golgi intermediate compartment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein RER1
    Names
    RER1 retention in endoplasmic reticulum 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362981.1NP_001349910.1  protein RER1

      Status: VALIDATED

      Source sequence(s)
      AL670413
      Consensus CDS
      CCDS19022.1
      UniProtKB/Swiss-Prot
      Q3THP4, Q9CQU3
      Related
      ENSMUST00000149796.2
      Conserved Domains (1) summary
      pfam03248
      Location:20185
      Rer1; Rer1 family
    2. NM_026395.2NP_080671.1  protein RER1

      See identical proteins and their annotated locations for NP_080671.1

      Status: VALIDATED

      Source sequence(s)
      AK002550, BM898853, BY164316
      Consensus CDS
      CCDS19022.1
      UniProtKB/Swiss-Prot
      Q3THP4, Q9CQU3
      Related
      ENSMUSP00000030914.4, ENSMUST00000030914.4
      Conserved Domains (1) summary
      pfam03248
      Location:20185
      Rer1; Rer1 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      155158566..155170840 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250328.4XP_011248630.1  protein RER1 isoform X1

      See identical proteins and their annotated locations for XP_011248630.1

      UniProtKB/Swiss-Prot
      Q3THP4, Q9CQU3
      Conserved Domains (1) summary
      pfam03248
      Location:20185
      Rer1; Rer1 family
    2. XM_006539131.4XP_006539194.1  protein RER1 isoform X1

      See identical proteins and their annotated locations for XP_006539194.1

      UniProtKB/Swiss-Prot
      Q3THP4, Q9CQU3
      Conserved Domains (1) summary
      pfam03248
      Location:20185
      Rer1; Rer1 family
    3. XM_006539132.4XP_006539195.1  protein RER1 isoform X1

      See identical proteins and their annotated locations for XP_006539195.1

      UniProtKB/Swiss-Prot
      Q3THP4, Q9CQU3
      Conserved Domains (1) summary
      pfam03248
      Location:20185
      Rer1; Rer1 family
    4. XM_030253730.1XP_030109590.1  protein RER1 isoform X1

      UniProtKB/Swiss-Prot
      Q3THP4, Q9CQU3
      Conserved Domains (1) summary
      pfam03248
      Location:20185
      Rer1; Rer1 family
    5. XM_006539133.4XP_006539196.1  protein RER1 isoform X1

      See identical proteins and their annotated locations for XP_006539196.1

      UniProtKB/Swiss-Prot
      Q3THP4, Q9CQU3
      Conserved Domains (1) summary
      pfam03248
      Location:20185
      Rer1; Rer1 family