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    Sec22c SEC22 homolog C, vesicle trafficking protein [ Mus musculus (house mouse) ]

    Gene ID: 215474, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Sec22cprovided by MGI
    Official Full Name
    SEC22 homolog C, vesicle trafficking proteinprovided by MGI
    Primary source
    MGI:MGI:2447871
    See related
    Ensembl:ENSMUSG00000061536 AllianceGenome:MGI:2447871
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sec22l3; 4932412K21; C530046H07; 5930407I15Rik
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human SEC22C (SEC22 homolog C, vesicle trafficking protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in thymus adult (RPKM 5.4), duodenum adult (RPKM 4.2) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Sec22c in Genome Data Viewer
    Location:
    9 F4; 9 72.54 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (121509111..121534614, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (121680045..121705548, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene lysozyme-like 4 Neighboring gene lysozyme-like 4, opposite strand Neighboring gene STARR-seq mESC enhancer starr_25538 Neighboring gene vasoactive intestinal peptide receptor 1 Neighboring gene STARR-positive B cell enhancer ABC_E10592 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:121591571-121591680 Neighboring gene STARR-positive B cell enhancer mm9_chr9:121606658-121606959 Neighboring gene STARR-positive B cell enhancer ABC_E11426 Neighboring gene STARR-positive B cell enhancer ABC_E1400 Neighboring gene STARR-positive B cell enhancer ABC_E10593 Neighboring gene SS18, nBAF chromatin remodeling complex subunit like 2 Neighboring gene natural killer tumor recognition sequence Neighboring gene RIKEN cDNA E530011L22 gene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    vesicle-trafficking protein SEC22c
    Names
    SEC22 vesicle trafficking protein homolog C
    SEC22 vesicle trafficking protein-like 3
    SEC22 vesicle trafficking protein-like C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164562.1 → NP_001158034.1  vesicle-trafficking protein SEC22c

      See identical proteins and their annotated locations for NP_001158034.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC159810, AK044249, BC046289, CJ247427
      Consensus CDS
      CCDS23634.1
      UniProtKB/Swiss-Prot
      Q8BMH4, Q8BXT9, Q8C0R8
      Related
      ENSMUSP00000107185.3, ENSMUST00000111560.10
      Conserved Domains (1) summary
      cd14824
      Location:5 → 123
      Longin; longin domain

    2. NM_178677.4 → NP_848792.2  vesicle-trafficking protein SEC22c

      See identical proteins and their annotated locations for NP_848792.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC159810, BB661643, BC046289, CJ247427
      Consensus CDS
      CCDS23634.1
      UniProtKB/Swiss-Prot
      Q8BMH4, Q8BXT9, Q8C0R8
      Related
      ENSMUSP00000077628.5, ENSMUST00000078547.12
      Conserved Domains (1) summary
      cd14824
      Location:5 → 123
      Longin; longin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      121509111..121534614 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512043.5 → XP_006512106.1  vesicle-trafficking protein SEC22c isoform X1

      See identical proteins and their annotated locations for XP_006512106.1

      UniProtKB/Swiss-Prot
      Q8BMH4, Q8BXT9, Q8C0R8
      Conserved Domains (1) summary
      cd14824
      Location:5 → 123
      Longin; longin domain

    2. XM_006512042.5 → XP_006512105.1  vesicle-trafficking protein SEC22c isoform X1

      See identical proteins and their annotated locations for XP_006512105.1

      UniProtKB/Swiss-Prot
      Q8BMH4, Q8BXT9, Q8C0R8
      Conserved Domains (1) summary
      cd14824
      Location:5 → 123
      Longin; longin domain

    3. XM_030244233.2 → XP_030100093.1  vesicle-trafficking protein SEC22c isoform X3

    4. XM_006512044.5 → XP_006512107.1  vesicle-trafficking protein SEC22c isoform X2

      Conserved Domains (1) summary
      cd14824
      Location:5 → 123
      Longin; longin domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BXT9.1 GenPept UniProtKB/Swiss-Prot:Q8BXT9

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