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    Edrf1 erythroid differentiation regulatory factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 214764, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Edrf1provided by MGI
    Official Full Name
    erythroid differentiation regulatory factor 1provided by MGI
    Primary source
    MGI:MGI:1919831
    See related
    Ensembl:ENSMUSG00000039990 AllianceGenome:MGI:1919831
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2700050L05Rik
    Summary
    Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human EDRF1 (erythroid differentiation regulatory factor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 5.7), CNS E14 (RPKM 5.2) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Edrf1 in Genome Data Viewer
    Location:
    7 F3; 7 77.18 cM
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (133239422..133274710)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (133637544..133673017)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene testis expressed 36 Neighboring gene predicted gene, 35625 Neighboring gene STARR-positive B cell enhancer ABC_E2851 Neighboring gene matrix metallopeptidase 21 Neighboring gene uroporphyrinogen III synthase Neighboring gene STARR-positive B cell enhancer ABC_E4982 Neighboring gene STARR-positive B cell enhancer ABC_E10481 Neighboring gene BRCA2 and CDKN1A interacting protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC27934, MGC58090

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    erythroid differentiation-related factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001408042.1 → NP_001394971.1  erythroid differentiation-related factor 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC127348

    2. NM_001408043.1 → NP_001394972.1  erythroid differentiation-related factor 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC127348
      UniProtKB/TrEMBL
      D3YZE7
      Related
      ENSMUSP00000115641.3, ENSMUST00000128901.9

    3. NM_001408044.1 → NP_001394973.1  erythroid differentiation-related factor 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC127348

    4. NM_178115.5 → NP_835216.3  erythroid differentiation-related factor 1 isoform 1

      See identical proteins and their annotated locations for NP_835216.3

      Status: VALIDATED

      Source sequence(s)
      AC127348
      Consensus CDS
      CCDS21932.2
      UniProtKB/Swiss-Prot
      Q6GQV7, Q80ZY3, Q8R3P5
      UniProtKB/TrEMBL
      E9Q9F9
      Related
      ENSMUSP00000059166.7, ENSMUST00000051169.13

    RNA

    1. NR_176447.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC127348

    2. NR_176448.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC127348

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      133239422..133274710
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_145995.1: Suppressed sequence

      Description
      NM_145995.1: This RefSeq was temporarily suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6GQV7.1 GenPept UniProtKB/Swiss-Prot:Q6GQV7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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