|
| Status |
Public on Nov 23, 2007 |
| Title |
Prediction of breast cancer pathological complete response to anthracycline/taxane chemotherapy. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
EORTC 10994 phase III breast cancer clinical trial comparing FEC (5-fluorouracil, cyclophosphamide, epirubicin) with ET (epirubicin, docetaxel). 161 needle biopsies of locally advanced or large operable breast tumours were hybridised to Affymetrix X3P chips. The array data from the ER negative tumours (28/65 pathological CR in the FEC arm, 27/59 pathological CR in the ET arm) were used to validate the cell line-based chemotherapy response predictors developed by the Potti/Nevins group at Duke University (doi:10.1038/nm1491).
Keywords: Tumour profiling
|
| |
|
| Overall design |
We analyzed 161 arrays of breast carcinoma.
|
| |
|
| Contributor(s) |
Farmer P, Bonnefoi H, Iggo R |
| Citation(s) |
18024211, 25601208 |
| |
| Submission date |
Jan 25, 2007 |
| Last update date |
Jun 06, 2022 |
| Contact name |
Richard Iggo |
| E-mail(s) |
r.iggo@bordeaux.unicancer.fr
|
| Phone |
+33 5 56 33 04 23
|
| Fax |
+33 5 56 33 32 06
|
| Organization name |
University of Bordeaux
|
| Department |
Bergonie Cancer Institute
|
| Lab |
INSERM U916
|
| Street address |
229 cours de l'Argonne
|
| City |
Bordeaux |
| ZIP/Postal code |
33076 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL1352 |
[U133_X3P] Affymetrix Human X3P Array |
|
| Samples (161)
|
|
| Relations |
| BioProject |
PRJNA99107 |
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