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Status |
Public on Dec 01, 2014 |
Title |
Blood gene expression profiles associated with symptoms of generalized anxiety disorder |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Prospective epidemiological studies found that generalized anxiety disorder (GAD) can impair immune function and increase risk for cardiovascular disease or events. Mechanisms underlying the physiological reververations of anxiety, however, are still elusive. Hence, we aimed to investigate molecular processes mediating effects of anxiety on physical health using blood gene expression profiles of 546 community participants. Of these, 179 met the status of controls and 157 cases of anxiety.
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Overall design |
We examined genome-wide differential gene expression in anxiety, as well as associations between nine major modules of co-regulated transcripts in blood gene expression and anxiety. There were a total of 546 subjects.
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Contributor(s) |
Wingo AP, Gibson G |
Citation(s) |
25300922, 26849112 |
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Submission date |
Sep 23, 2014 |
Last update date |
Jan 07, 2021 |
Contact name |
Aliza P. Wingo |
Organization name |
Atlanta VAMC/Emory University
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Department |
Psychiatry
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Street address |
1670 Clairmont Rd
|
City |
Decatur |
State/province |
GA |
ZIP/Postal code |
30033 |
Country |
USA |
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Platforms (1) |
GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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Samples (546)
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Relations |
BioProject |
PRJNA261818 |