|
Status |
Public on Sep 02, 2009 |
Title |
Chronic myeloid leukemia CML-#16-CP-250knsp |
Sample type |
genomic |
|
|
Source name |
Chronic phase
|
Organism |
Homo sapiens |
Characteristics |
Bone marrow
|
Treatment protocol |
Samples were obtained at different stages of disease
|
Growth protocol |
Cryopreserved peripheral blood or bone marrow samples obtained at diagnosis, during disease progression, or after treatment. Blast crisis samples were flow sorted prior to DNA extraction.
|
Extracted molecule |
genomic DNA |
Extraction protocol |
Qiagen DNA blood mini or phenol chloroform
|
Label |
Biotin
|
Label protocol |
As per manufacturer (Affymetrix)
|
|
|
Hybridization protocol |
As per manufacturer (Affymetrix)
|
Scan protocol |
As per manufacturer (Affymetrix)
|
Description |
Chronic myeloid leukemia
|
Data processing |
CEL files and TXT files (generated by Affymetrix GTYPE using the DM algorithm) were processed by dChip and model-based expression performed using the PM/MM model. Normalization was performed using the reference normalization algorithm developed at St Jude and described in Mullighan et al Nature 2007;446:758. The data matrix contains the normalized expression values produced by that algorithm.
|
|
|
Submission date |
Oct 10, 2007 |
Last update date |
Sep 02, 2009 |
Contact name |
Charles G Mullighan |
E-mail(s) |
charles.mullighan@stjude.org
|
Phone |
1-901-595-3387
|
Organization name |
St Jude Children's Research Hospital
|
Department |
Pathology
|
Street address |
262 Danny Thomas Place
|
City |
Memphis |
State/province |
TN |
ZIP/Postal code |
38105 |
Country |
USA |
|
|
Platform ID |
GPL3718 |
Series (2) |
GSE9110 |
SNP array data for 56 chronic myeloid leukemia samples. |
GSE9113 |
Affymetrix SNP array data for acute lymphoblastic leukemia samples |
|