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Sample GSM1619452 Query DataSets for GSM1619452
Status Public on Oct 06, 2015
Title sample_53_08-GC-001 [expression]
Sample type RNA
 
Source name Breast cancer, CHER-LOB Arm B, pre-treated
Organism Homo sapiens
Characteristics disease state: HER2-positive breast cancer
tissue: breast cancer
cher-lob arm: B
arm description: chemotherapy+lapatinib
pcr (1=yes): 0
Treatment protocol CHER-LOB is a phase II, randomized, multicenter, trial in which 121 patients with primary HER2-positive breast cancer were randomized to receive preoperative chemotherapy with weekly paclitaxel times 12 followed by 4 courses of 3-weekly FEC (fluorouracil, epirubicin and cyclophosphamide) plus either trastuzumab (Arm A), lapatinib (Arm B) or the combination of trastuzumab and lapatinib (Arm C). The trial design, eligibility criteria, statistical analysis, and clinical results including response, surgery outcomes and treatment safety are described in details elsewhere.
Growth protocol NA
Extracted molecule total RNA
Extraction protocol Qiagen RNeasy (manufacturer's protocol).
Label Biotin
Label protocol Affymetrix GeneChip® 3' IVT Express Kit (manufacturer's protocol).
 
Hybridization protocol Affymetrix Human Genome U133 Plus 2.0 array (manufacturer's protocol).
Scan protocol Affymetrix GeneChip Scanner 3000 7G (manufacturer's protocol).
Data processing Partek GS.
 
Submission date Feb 25, 2015
Last update date Jun 06, 2022
Contact name Enrico Tagliafico
E-mail(s) enrico.tagliafico@unimore.it
Organization name University of Modena and Reggio Emilia
Department Center for Genome Research
Street address Via Campi 287
City Modena
State/province MO
ZIP/Postal code 41126
Country Italy
 
Platform ID GPL570
Series (2)
GSE66305 Prospective biomarker analysis of the randomized CHER-LOB study evaluating the dual anti-HER2 treatment with chemotherapy plus trastuzumab and lapatinib as neoadjuvant therapy for HER2-positive breast cancer [expression]
GSE66399 Prospective biomarker analysis of the randomized CHER-LOB study evaluating the dual anti-HER2 treatment with chemotherapy plus trastuzumab and lapatinib as neoadjuvant therapy for HER2-positive breast cancer
Relations
Reanalyzed by GSE205568

Data table header descriptions
ID_REF
VALUE RMA signal

Data table
ID_REF VALUE
1007_s_at 10.7652
1053_at 7.59171
117_at 5.85353
121_at 6.88288
1255_g_at 2.45888
1294_at 7.27548
1316_at 7.08793
1320_at 4.25549
1405_i_at 8.95515
1431_at 3.87506
1438_at 6.37797
1487_at 6.87836
1494_f_at 4.53778
1552256_a_at 7.2301
1552257_a_at 7.92156
1552258_at 4.26918
1552261_at 3.59765
1552263_at 5.75276
1552264_a_at 5.98897
1552266_at 4.1045

Total number of rows: 54675

Table truncated, full table size 998 Kbytes.




Supplementary file Size Download File type/resource
GSM1619452_53_08-GC-001_HG-U133_Plus_2_.CEL.gz 4.5 Mb (ftp)(http) CEL
Processed data included within Sample table

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